Oral Composition Raising Oxidation-Reduction Potential to Inhibit Putrefaction
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Solution Overview
Problem
Existing oral care products have not effectively addressed the common process of oral bacterial putrefaction, which leads to gingivitis, periodontitis, and oral malodor, by simultaneously lowering the oxidation-reduction potential (Eh) and failing to create an oral environment that inhibits these conditions.
Innovation Solution
An oral composition comprising at least one Eh-raising compound and at least one zinc compound, along with cetylpyridinium chloride (CPC), is used to inhibit the formation of sulfur-containing compounds, reduce oral malodor and gingivitis, and prevent the reduction of the oxidation-reduction potential in the oral cavity.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If germicidal agents are used to treat gingivitis-periodontitis and oral malodor, then bacterial growth is inhibited, but the oxidation-reduction potential (Eh) is lowered and putrefaction is not effectively prevented
Solution Approach 1:
The patent applies parameter changes by modifying the oxidation-reduction potential (Eh) of the oral environment through zinc compounds and CPC. This shifts the chemical parameter of the oral cavity to a state that is inhospitable to putrefactive bacteria, thereby preventing the formation of malodorous compounds without relying solely on germicidal action.
Solution Approach 2:
The patent creates an inert oral environment by raising the Eh to levels that prevent anaerobic bacterial activity. This establishes a chemical atmosphere in the oral cavity that is non-conducive to putrefaction, effectively isolating the bacterial populations from conditions that enable harmful metabolic processes.
2Productivity
If oral care products focus on germicidal action, then bacterial killing is achieved, but the underlying putrefaction process is not addressed
Solution Approach 1:
The patent converts the harmful anaerobic environment into a beneficial aerobic environment by raising the Eh. This transforms the oral cavity from a state that promotes putrefaction to one that supports healthy bacterial populations, turning the previously harmful chemical conditions into a protective factor against disease.
3Reliability
If the oral environment maintains low Eh, then bacterial growth is controlled, but putrefaction continues and oral diseases persist
Solution Approach 1:
The patent fundamentally changes the Eh parameter of the oral environment to prevent the formation of sulfur-containing compounds. By maintaining a high Eh through zinc and CPC, the chemical conditions no longer support the metabolic pathways that produce these harmful putrefaction end-products.
Data Source
AI summary
Oral compositions and methods of use thereof are provided herein. The oral compositions comprise a first component comprising at least one Eh-raising compound and a pharmaceutically acceptable carrier, and a second component comprising at least one zinc compound, an anti-microbial agent and a pharmaceutically acceptable carrier.