Oral Immunotherapy Dosing System with Segmented Containers

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Solution Overview

Problem

Current oral immunotherapy dosing regimens are complex and prone to errors, requiring precise dosing to ensure efficacy and safety, particularly in treating serious food allergies, where incorrect dosages can lead to adverse reactions.

Innovation Solution

A system comprising a housing with multiple dosage containers, each containing single dose packages of varying oral immunotherapy compositions, identified by dosage identifiers such as color-coding, numeric coding, or capsule configuration, to facilitate accurate selection and administration of appropriate dosages, reducing the risk of errors.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If multiple dosage containers with different dosages are used, then dosing precision is improved, but device complexity increases

Engineering Contradiction:
Improvedosing precisionVSAvoiddevice complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The system divides the immunotherapy dosing system into multiple separate dosage containers, each dedicated to a specific dosage level. Each container is further segmented into individual single-use packets. This segmentation allows for precise dosing selection while organizing complexity into manageable, discrete units that reduce selection errors.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

Each dosage container is assigned specific identifying characteristics (color-coding, numeric coding, capsule configuration) that are locally optimized for its specific dosage level. This allows users to quickly identify and select the correct dosage without having to examine all containers, reducing complexity in the selection process while maintaining high dosing precision.

Inventive Principle:
Principle #3Local quality

2Ease of operation

If dosage identifiers such as color-coding are implemented, then ease of operation is improved, but manufacturing complexity increases

Engineering Contradiction:
Improveease of operationVSAvoidmanufacturing complexity
Core Design Contradiction:
Ease of operationVSEase of manufacture

Solution Approach 1:

The system implements color-coding on dosage containers and/or capsules to provide immediate visual identification of dosage levels. This dramatically improves ease of operation by allowing patients and providers to quickly select the correct dosage. The manufacturing complexity is managed by applying color codes during standard packaging processes, which are scalable and can be integrated into existing manufacturing lines.

Inventive Principle:
Principle #32Color changes

Solution Approach 2:

Different identification methods (color-coding, numeric coding, capsule configuration) are applied locally to different dosage containers based on their specific dosage levels. This allows the system to optimize for ease of operation with multiple identification modalities while managing manufacturing complexity by applying these identifiers through established packaging and labeling technologies.

Inventive Principle:
Principle #3Local quality

3Reliability

If single dose packages are used for each dosage, then reliability is improved, but loss of substance increases

Engineering Contradiction:
Improvedosing reliabilityVSAvoidmedication waste
Core Design Contradiction:
ReliabilityVSLoss of substance

Solution Approach 1:

The system segments the total medication supply into individual single-use packets within each dosage container. This ensures that only the exact dosage needed is dispensed at each administration, eliminating the risk of contamination or incorrect dosing from partially used containers. The segmentation enables precise tracking of medication usage and reduces waste by allowing patients to take exactly what is prescribed without needing to manage larger multi-dose containers.

Inventive Principle:
Principle #1Segmentation

Data Source

PatentUS11406563B2Oral immunotherapy unit dose dispensing systems and methods
Publication Date: 2022.08.09 SOCIETE DES PRODUITS NESTLE SA
  • US11406563B2 patent drawing
  • US11406563B2 patent drawing
  • US11406563B2 patent drawing

AI summary

Systems and containers for organizing and administering an oral immunotherapy regimen to a patient are disclosed herein. One aspect of the present technology is directed systems for efficiently and safely identifying pre-packaged dose units to administer to a patient undergoing oral immunotherapy. Further aspects of the present technology are directed to reducing medical staff dosing errors when administering an oral immunotherapy regimen. In one embodiment, the system includes a plurality of dosage containers, wherein each dosage container includes dosage identification characteristics corresponding to dosage of an oral immunotherapy composition. Further aspects of the present technology are directed to methods of dispensing an oral immunotherapy composition to a patient in a manner that mitigates the risk of errors in oral immunotherapy dose administration.