Oriental Medicine Composition for Thyroid Hormone Normalization

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Solution Overview

Problem

Conventional treatments for thyroid diseases like hypothyroidism, such as levothyroxine supplementation, often result in side effects and do not fully eliminate symptoms, leading to a need for alternative therapies that can normalize thyroid hormone levels effectively without adverse effects.

Innovation Solution

An oriental medicine composition comprising Rehmanniae Radix Preparata, Angelicae Gigantis Radix, Lycii Fructus, Paeoniae Radix, and Dioscoreae Rhizoma, which may also include additional herbs like Bupeuri Radix and Glycyrrhizae Radix et Rhizoma, is used to normalize thyroid hormone levels, providing sustained thyroid hormone concentration without side effects.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If levothyroxine is administered to normalize thyroid hormone levels, then thyroid hormone levels can be maintained, but side effects such as vomiting, diarrhea, or headache occur and some symptoms like neurologic disorders are not entirely eliminated

Engineering Contradiction:

Improvethyroid hormone level normalizationVSAvoidside effects and residual symptoms

Core Design Contradiction:

ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent uses a multi-herb oriental medicine composition as an intermediary substance to regulate thyroid function. The composition includes Rehmanniae Radix Preparata, Angelicae Gigantis Radix, Lycii Fructus, Paeoniae Radix, and Dioscoreae Rhizoma, which work together to modulate thyroid hormone levels naturally without the harsh side effects of synthetic levothyroxine, serving as a mediator between the body's natural thyroid function and the need for hormone supplementation

Inventive Principle:

Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent changes the chemical and pharmacological parameters of thyroid treatment by replacing synthetic levothyroxine with a natural herb-based composition. The oriental medicine formulation alters the mode of action from direct hormone replacement to a more gradual, multi-component regulation that adjusts thyroid function through traditional herbal mechanisms, thereby reducing side effects while maintaining efficacy

Inventive Principle:

Principle #35Parameter changes

2Object-affected harmful factors

If exact dosage of levothyroxine is maintained to avoid side effects, then side effects are reduced, but the treatment complexity and monitoring requirements increase

Engineering Contradiction:

Improveside effectsVSAvoiddosage control and monitoring

Core Design Contradiction:

Object-affected harmful factorsVSDevice complexity

Solution Approach 1:

The oriental medicine composition is designed to be self-regulating in terms of dosage and effect. The multi-herb formulation works synergistically to naturally adjust thyroid hormone levels according to the body's needs, reducing the need for precise dosage control and frequent monitoring that characterizes levothyroxine therapy, thereby simplifying the treatment regimen while maintaining effectiveness

Inventive Principle:

Principle #25Self-service

Data Source

PatentUS11478523B2Oriental medicine composition effective for thyroid hormone level normalization

Publication Date: 2022.10.25 KIM HYONG JUN

AI summary

The present disclosure relates to an oriental medicine composition effective for thyroid hormone level normalization, and more particularly, to an oriental medicine composition for treating thyroid diseases, such as hypothyroidism or hyperthyroidism.