Multidimensional Cardiac Analysis Device Using Orthogonal ECG and Impedance

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Current devices lack the capability to simultaneously measure the time course of cardiac contraction and its stimulation, and there is no device that performs vectorcardiography and three-dimensional cardiac impedance measurements, which are essential for comprehensive cardiac activity analysis, especially in non-invasive and affordable ways.

Innovation Solution

A method and device for multidimensional analysis of cardiac activity that combines simultaneous three-dimensional ECG and impedance rheometry measurements, using electrodes on three orthogonal axes with different current frequencies, along with tissue motion sensors for non-invasive monitoring of cardiac tissue dynamics, allowing for the assessment of energy and work related to myocardium activity.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If echocardiography, magnetic resonance, computer tomography, or nuclear medicine methods are used to observe contraction time course, then measurement precision is improved, but device complexity and cost increase significantly

Engineering Contradiction:
Improvecontraction time course measurementVSAvoidequipment complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent combines ECG measurements with impedance rheometry measurements into a single integrated system. The ECG electrodes serve dual purposes: detecting electrical cardiac activity and measuring impedance changes. This merging of functions allows simultaneous acquisition of contraction timing and mechanical activity data without requiring separate expensive imaging equipment like echocardiography or MRI machines.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The measurement system is designed to perform multiple functions using the same hardware components. The electrodes placed on the patient's body serve both as ECG sensors for electrical activity detection and as impedance measurement points for mechanical activity assessment. This multi-functionality eliminates the need for specialized equipment for each measurement type, reducing overall system complexity and cost.

Inventive Principle:
Principle #6Universality (Multi-functionality)

2Measurement precision

If vectorcardiography and three-dimensional cardiac impedance measurements are performed simultaneously, then measurement precision is improved, but device complexity increases

Engineering Contradiction:
Improvecardiac activity analysisVSAvoidmeasurement system complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The measurement system is divided into three orthogonal measurement axes (X, Y, Z), each with its own pair of electrodes. This segmentation into independent orthogonal components allows the system to capture three-dimensional cardiac activity separately along each axis, which can then be synthesized to provide comprehensive spatial information about cardiac function without requiring a single complex three-dimensional sensor array.

Inventive Principle:
Principle #1Segmentation

3Device complexity

If classical electrocardiography with impedance measurement is used for navigation during heart ablation, then device complexity is reduced, but measurement precision is insufficient because only resistance is measured and heart rate synchronous averaging is required

Engineering Contradiction:
Improvemeasurement system simplicityVSAvoidcardiac activity measurement
Core Design Contradiction:
Device complexityVSMeasurement precision

Solution Approach 1:

The patent applies periodic current at different frequencies through the impedance measurement system. By using alternating current at multiple frequencies rather than direct current, the system can differentiate between resistive and reactive components of tissue impedance. This periodic action enables real-time measurement of both resistance and reactance without requiring signal averaging, providing more precise cardiac activity data while maintaining system simplicity.

Inventive Principle:
Principle #19Periodic action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables advanced, non-invasive, and automated diagnostics of heart diseases by providing a holistic view of cardiac motion and energy dynamics, differentiating healthy from diseased states with high efficiency, potentially available in every clinic.

Implementation Method 1

The measurement applies to tissues that move in the chest, such as contractile tissues (muscles) and those that are moved by the contractile tissues

Methodology Applied
Scientific EffectElectrical Impedance: Electrical Resistance

Implementation Method 2

the impedance rheometry measurement comprises simultaneous generation of applied current of different frequencies for three orthogonal axes

Methodology Applied
Scientific EffectElectrical Conduction: Conduction (electrical)

Data Source

PatentUS20230210393A1Method and device for multidimensional analysis of the dynamics of cardiac activity
Publication Date: 2023.07.06 EFM SA
  • US20230210393A1 patent drawing
  • US20230210393A1 patent drawing
  • US20230210393A1 patent drawing

AI summary

The present disclosure relates to a method for measuring multidimensional dynamics of cardiac activity comprising simultaneous measurement ofthree dimensional ECG,three dimensional impedance rheometry,tissue motion, wherein the tissue motion measurement is performed with a sensor placed outside the patient body selected from among sensors including: membrane, auscultation funnel, accelerometer, microphone, piezoelectric sensor,wherein the impedance rheometry measurement includes simultaneous generation of applied current of different frequencies for three orthogonal axes and an impedance measurement for the same or other three orthogonal axes, andwherein the impedance rheometry measurement and the ECG measurement are carried out for the same three orthogonal axes.The present disclosure further relates to a device for implementation of the method.