Orthogonal Cutting Blade for Uniform Tissue Fragments

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Solution Overview

Problem

Current methods in regenerative medicine face challenges in efficiently producing uniform, minute tissue fragments from biological tissues for grafting, as existing cutting devices struggle with soft and fragile tissues, leading to low survival rates and inefficient regeneration.

Innovation Solution

A biological tissue cutting device with a stage unit and dual cutting units that form cut surfaces in orthogonal directions, allowing for simultaneous cutting in multiple planes to produce uniform tissue fragments, thereby improving the yield and efficiency of tissue fragment production.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Speed

If a laser beam cutting device is used to cut biological tissue, then cutting speed is improved, but the device cannot effectively cut soft and fragile wet tissues into minute fragments

Engineering Contradiction:

Improvecutting speedVSAvoidability to cut soft wet tissue

Core Design Contradiction:

SpeedVSAdaptability or versatility

Solution Approach 1:

The patent replaces the laser beam cutting system with a mechanical cutting system using a cutting blade that physically contacts and cuts the biological tissue. This mechanical approach is specifically suited for soft, wet tissues as it provides direct control over the cutting action and can handle the fragility of such tissues effectively.

Inventive Principle:

Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The cutting process is segmented into multiple directional cuts (first direction, second direction, third direction) performed by different cutting units. This segmentation allows the tissue to be systematically divided into minute fragments through sequential cutting actions in orthogonal directions, making the overall process manageable and effective for soft tissues.

Inventive Principle:

Principle #1Segmentation

2Manufacturing precision

If manual cutting is performed by skilled persons to produce tissue fragments, then uniformity of tissue fragments is improved, but operation efficiency deteriorates

Engineering Contradiction:

Improveuniformity of tissue fragmentsVSAvoidoperation efficiency

Core Design Contradiction:

Manufacturing precisionVSProductivity

Solution Approach 1:

The cutting blade is designed to be movable in multiple directions (first, second, and third directions) rather than fixed. This dynamic capability allows the single blade to perform multiple cutting operations that would otherwise require multiple fixed blades or manual repositioning, thereby maintaining uniformity while improving efficiency.

Inventive Principle:

Principle #15Dynamics

Solution Approach 2:

The cutting blade serves multiple functions by being capable of cutting in three orthogonal directions. This multi-functionality replaces what would traditionally require multiple separate cutting tools or manual operations, enabling one device to produce uniform minute fragments efficiently.

Inventive Principle:

Principle #6Universality (Multi-functionality)

3Productivity

If multiple cutting units are added to cut in orthogonal directions, then productivity is improved, but device complexity increases

Engineering Contradiction:

Improvenumber of tissue fragments producedVSAvoidnumber of cutting units

Core Design Contradiction:

ProductivityVSDevice complexity

Solution Approach 1:

Instead of adding multiple fixed cutting units, the patent employs a single cutting blade that is dynamically movable in multiple directions. This dynamic approach achieves the productivity of multiple cutting units while avoiding their structural complexity, as one movable blade replaces what would otherwise require three or more fixed blades.

Inventive Principle:

Principle #15Dynamics

Solution Approach 2:

The patent merges the functionality of multiple cutting units into a single cutting blade that can operate in multiple directions. By combining these functions into one component, the device achieves high productivity without the complexity of multiple separate cutting units, as the single blade performs all cutting operations in orthogonal directions.

Inventive Principle:

Principle #5Merging (Combining)

Data Source

PatentUS10036689B2Biological tissue cutting device and use thereof

Publication Date: 2018.07.31 JMS CO LTD

AI summary

The present invention provides a biological tissue cutting device that can produce minute fragments of a biological tissue easily and efficiently. The biological tissue cutting device for producing tissue fragments by cutting a biological tissue includes: a first cutting unit configured to form a cut surface extending in a first direction by cutting the biological tissue on a stage; and a second cutting unit configured to form a cut surface extending in a second direction and a cut surface extending in a third direction by cutting the biological tissue on the stage. The planar direction of the cut surface extending in the second direction is a direction crossing the cut surface extending in the first direction, and the planar direction of the cut surface extending in the third direction is a direction crossing the cut surface extending in the first direction and the cut surface extending in the second direction.