Orthogonal Fiber Thrombus Removal Device
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Existing devices for removing thrombi from blood vessels are inadequate for completely removing thrombi from small-lumen vessels and often risk releasing thrombus fragments into smaller vessels, due to their size and inflexibility, and require complex cooling or heating mechanisms.
Innovation Solution
A device with a distal element featuring orthogonal fibers or bristles, made from materials like polymer, metal, or ceramic, which can be arranged in bundles and connected to a guide wire, allowing for flexible navigation and secure thrombus capture and removal through a micro-catheter, with optional thrombogeneous coatings for enhanced adherence.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Adaptability or versatility
If prior art devices are used for thrombus removal, then thrombus can be removed from large vessels, but the devices are too large and inflexible for small-lumen vessels
Solution Approach 1:
The distal element with orthogonal fibers is nested within a catheter during delivery, allowing the device to pass through small-lumen vessels. Upon deployment, the fibers extend radially outward to capture thrombus. This nested configuration enables the device to adapt to small vessel diameters while maintaining the functionality to capture and remove thrombi.
Solution Approach 2:
The device transitions from a compressed, low-profile state during delivery to an expanded, high-capture-state during thrombus removal. The orthogonal fibers can dynamically adjust their configuration - compressed within the catheter for navigation through small vessels, then extended for effective thrombus capture and retrieval.
2Reliability
If prior art devices are used for thrombus removal, then some thrombus can be removed, but complete removal is impossible and fragments may be released into the bloodstream
Solution Approach 1:
The distal element features orthogonal fibers distributed across its surface, creating multiple localized capture points throughout the device structure. This distributed fiber arrangement enables complete engulfment and secure capture of the entire thrombus, preventing fragment release during retrieval through the catheter and into the bloodstream.
Solution Approach 2:
The device is designed to fully capture and secure the thrombus before retrieval begins. The orthogonal fiber structure预先 establishes a secure envelope around the thrombus, ensuring complete containment and preventing fragmentation or release during the subsequent withdrawal process.
3Reliability
If shape-memory capture arms are used to capture thrombus, then thrombus can be captured, but complex cooling or heating mechanisms are required
Solution Approach 1:
The orthogonal fibers are made of thrombogeneous materials that inherently promote thrombus adherence and capture through their surface properties and structural configuration. The device leverages the natural thrombogenicity of the fiber materials and the mechanical interlocking capability of the orthogonal structure to capture thrombus without requiring external cooling or heating systems.
Solution Approach 2:
The invention replaces the thermal phase-change mechanism (shape-memory alloy requiring heating/cooling) with a purely mechanical capture system. The orthogonal fiber structure provides thrombus capture through mechanical interlocking and surface adhesion, eliminating the need for complex thermal control systems while maintaining reliable thrombus capture.
Data Source
AI summary
The invention relates to a device for the removal of foreign bodies and thrombi from body cavities and blood vessels using a guide wire provided with a distal element with said distal element being provided with an orthogonal structure.