OSA Screening System Using EHR Risk Scoring

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Solution Overview

Problem

Current screening methods for obstructive sleep apnea (OSA) are inefficient and often result in under-diagnosis due to the lack of clear symptoms in early onset cases, leading to high false positives and increased healthcare costs, as existing tools lack high validity and specificity.

Innovation Solution

A system that queries medical records to extract patient data, determines risk factors, calculates a total risk score using a logistic function, and assigns a risk category to predict the probability of OSA, thereby guiding follow-up procedures and reducing unnecessary diagnostic polysomnography.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If mass screening for OSA is performed using existing tools, then the number of OSA cases identified increases, but the false positive rate increases and healthcare costs increase

Engineering Contradiction:
ImproveOSA detection yieldVSAvoidscreening validity
Core Design Contradiction:
ProductivityVSReliability

Solution Approach 1:

The system performs preliminary risk assessment using electronic health record data before referring patients for formal OSA diagnosis. By pre-screening patients based on existing medical data (age, BMI, comorbidities, medications), the system identifies high-risk individuals who are most likely to have OSA, thereby increasing detection yield while reducing false positives by avoiding unnecessary screening of low-risk patients.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The system introduces an intermediary risk scoring algorithm that mediates between raw EHR data and formal OSA diagnosis. This intermediary layer processes multiple patient parameters through a logistic function to generate a risk score, which then guides referral decisions. This intermediary mechanism improves screening validity by objectively prioritizing patients based on calculated risk rather than subjective clinical judgment alone.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Measurement precision

If diagnostic polysomnography is performed on all suspected OSA cases, then diagnostic accuracy is maintained, but healthcare costs and waiting times increase

Engineering Contradiction:
ImproveOSA diagnosis accuracyVSAvoiddiagnostic waiting time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The diagnostic pathway is segmented into two distinct stages: (1) a preliminary risk assessment stage using easily obtainable EHR data to identify high-risk patients, and (2) a formal diagnostic stage using polysomnography only for those who exceed the risk threshold. This segmentation maintains diagnostic accuracy for high-risk patients while reducing overall system burden and waiting times by excluding low-risk patients from the lengthy polysomnography process.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

Instead of applying full diagnostic polysomnography to all suspected cases, the system applies partial action by using a simplified risk assessment tool for initial screening. This partial action is sufficient to identify high-risk patients who then receive the full diagnostic workup, thereby reducing overall diagnostic time and cost while maintaining accuracy for the subset of patients who truly need comprehensive evaluation.

Inventive Principle:
Principle #16Partial or excessive action

3Loss of time

If clinical screening tools are used to identify OSA risk factors, then early detection is improved, but the number of false positives increases due to lack of specificity

Engineering Contradiction:
Improvetime to detectionVSAvoidscreening specificity
Core Design Contradiction:
Loss of timeVSReliability

Solution Approach 1:

The system changes the parameters used for screening by incorporating multiple objective EHR data points (age, BMI, comorbidities, medications) into a unified risk score, rather than relying on a single subjective clinical questionnaire. By transforming these parameters through a logistic function, the system generates a continuous risk probability that improves specificity while maintaining early detection capability, as the mathematical model objectively weights each parameter's contribution to OSA risk.

Inventive Principle:
Principle #35Parameter changes

Data Source

PatentUS20240194355A1Assessing a subject's adherene to a treatment for a condition
Publication Date: 2024.06.13 KONINKLIJKE PHILIPS NV
  • US20240194355A1 patent drawing
  • US20240194355A1 patent drawing
  • US20240194355A1 patent drawing

AI summary

A screening system (100) including a controller (120, 190, 194) to: query data sources (142, 144, 146, 148, 150, 152) to extract medical status information (MSI) of a patient cohort; form patient cohort data (PCD) comprising records of the extracted MSI of the patients; exclude records that are disqualified according to exclusion rules (ERS), and update the PCD accordingly; determine risk factors that are present for each record in accordance with a comparison of the MSI for corresponding records with risk factors for obstructive sleep apnea (OSA); determine a total risk score for each in accordance with a total of the determined risk factors present; determine a predicted probability of OSA based upon the determined total risk score for each of the records; assign each to a risk category in accordance with risk thresholds applied to the predicted probability of OSA; and determine a follow-up procedure for each in accordance with the assigned risk category for the records.