Osteochondral Centrifugation System for Core Purification
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Current osteochondral core transplantation methods face challenges in reducing contamination and promoting healing, particularly due to the presence of blood and antigenic materials, which can impede successful integration and healing of the recipient site.
Innovation Solution
A centrifugation system is employed to process osteochondral cores, removing blood and potentially antigenic materials, and optionally infusing them with bioabsorbable materials and growth factors to enhance healing and reduce disease transmission risk.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If osteochondral cores are harvested and transplanted using conventional methods, then the transplantation procedure can be completed, but the cores contain blood and antigenic materials that cause contamination and impede healing
Solution Approach 1:
The patent applies centrifugation to extract and remove blood and antigenic materials from the osteochondral core. The core is placed in a centrifuge that separates and removes these harmful substances while preserving the viable cartilage and bone tissue, thereby reducing contamination and improving healing outcomes.
Solution Approach 2:
The patent performs centrifugation processing of the osteochondral core before transplantation into the recipient site. This preliminary cleaning action removes blood and antigenic materials in advance, preventing contamination and promoting better integration and healing at the transplant site.
2Reliability
If osteochondral cores are processed to remove blood and antigenic materials, then contamination is reduced and healing is promoted, but additional processing time and equipment are required
Solution Approach 1:
The patent replaces complex surgical cleaning procedures with a centrifugation system that uses centrifugal force to remove blood and antigenic materials. This mechanical substitution streamlines the processing procedure, making it more efficient and controllable while reducing overall processing time despite adding a centrifugation step.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The centrifugation system effectively cleans and enhances the osteochondral cores, improving their integration and healing outcomes by reducing contamination and promoting tissue repair.
Implementation Method 1
placing the osteochondral core in a centrifugation system, to remove blood or potentially antigenic or contaminating materials
Data Source
AI summary
An osteochondral centrifugation system for providing an osteochondral centrifuged core from a graft such as femoral condyle, for example. The centrifugation system may be used either in the operating room or, alternatively, at a tissue banking facility at the time of processing. The osteochondral centrifuged core is formed by (i) removing an osteochondral core from a graft; (ii) placing the osteochondral core in a centrifugation system to remove blood, lipids, or other potentially antigenic or contaminating materials, and to obtain a centrifuged core; and (iii) optionally, subjecting the centrifuged core to a material that reduces the chance of disease transmission and aids in the healing of the recipient site to which the centrifuged core is to be transferred.