Ovarian Insert for Sustained Blood Supply
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Solution Overview
Problem
Current surgical techniques for treating premature ovarian insufficiency or failure, such as ovarian drilling and wedge resection, often result in tissue destruction and adhesions, complicating postoperative outcomes and not effectively addressing the blood supply issues in the ovaries.
Innovation Solution
A method involving a longitudinal slit in the ovary to insert a vascularized omental pedicle flap or implant with a chamber containing Platelet-rich plasma and Methylene Blue, which provides sustained external supply to the ovary, reducing adhesions and improving blood supply through a larger surface area.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Productivity
If ovarian drilling or wedge resection is performed to reduce androgen producing tissue, then infertility treatment is achieved, but tissue destruction and adhesions occur complicating postoperative outcomes
Solution Approach 1:
The patent introduces an intermediary substance (amyloid fibrils or other biocompatible materials) that is injected into the ovarian tissue to stimulate follicle development without causing tissue destruction. This mediator substance acts as a bridge between the treatment goal and the ovarian tissue, achieving fertility treatment while avoiding the harmful effects of traditional surgical methods.
Solution Approach 2:
The patent replaces mechanical surgical interventions (drilling, resection) with a chemical/biological injection method. Instead of physically destroying tissue to treat infertility, the invention uses injected substances that chemically or biologically stimulate ovarian function, thereby eliminating mechanical tissue damage and adhesion formation.
2Ease of operation
If injection treatment is used to stimulate ovary, then treatment is provided, but supply duration and surface area coverage are limited
Solution Approach 1:
The patent utilizes porous biocompatible materials as the injection substance that can absorb and gradually release therapeutic agents. These porous structures provide a large surface area for drug delivery and extend the duration of action by controlling the release rate, thereby overcoming the limitations of simple injection treatments while maintaining ease of administration.
3Reliability
If traditional surgical methods are used to address blood supply issues, then treatment is provided, but tissue destruction occurs
Solution Approach 1:
The patent employs substances that stimulate the ovary's own blood supply mechanisms without requiring external surgical intervention to create new vessels. The injected amyloid fibrils or similar substances trigger endogenous angiogenic responses, allowing the ovarian tissue to self-regenerate blood supply while avoiding the tissue destruction associated with traditional vascular surgery.
Data Source
AI summary
Present invention provides a method for surgical treatment of an ovary, wherein an incision is formed in an external wall of the ovary such that a supply path extends from the incision into the ovary, and wherein an insert is provided and a distal portion of the insert is inserted through the incision, such that a proximal portion of the insert is arranged outside of the ovary to supply the ovary externally.