Oxygen Carrier System Stability in Silicone Formulations
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Solution Overview
Problem
Existing oxygen carrier systems for cosmetic and dermatologic applications face stability issues in silicone oil-containing formulations and require high concentrations to maintain effective oxygen release over time, limiting their effectiveness and usability.
Innovation Solution
A cosmetic and dermatologic oxygen carrier system comprising a liquid perfluorinated or partially fluorinated hydrocarbon, a liquid silicone polymer, and an oil or water base, with specific weight percentages and an initial oxygen loading method, allowing for increased oxygen release and stability without compromising formulation stability.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Ease of operation
If perfluorocarbon compounds are used as oxygen carriers in cosmetic formulations with silicone oils, then the formulation achieves light weight and non-stickiness properties, but the oxygen carrier concentration is limited to less than 5 percent by weight due to stability problems
Solution Approach 1:
The patent creates a composite oxygen carrier system combining perfluorocarbon compounds (0.1-10% by weight) with silicone polymer emulsions (10-85% by weight) and oil or water bases (5-25% by weight). This composite structure allows the oxygen carrier to function effectively at higher concentrations (1-40% by weight in final formulation) while maintaining stability in silicone oil-containing formulations, resolving the contradiction between formulation properties and oxygen carrier concentration.
2Duration of action of moving object
If high concentrations of oxygen carrier system (10-40 percent by weight) are used in silicone oil-free formulations, then oxygen release quantities over longer periods (8-40 weeks) are ensured, but the formulation complexity and stability control become more difficult
Solution Approach 1:
The silicone polymer emulsion acts as an intermediary carrier system that stabilizes the perfluorocarbon oxygen carrier. This intermediary structure enables high concentrations of oxygen carrier (10-40% by weight) to be incorporated while maintaining formulation stability over extended periods (8-40 weeks), resolving the contradiction between duration of action and formulation complexity.
3Stability of the object's composition
If lower concentrations of oxygen carrier systems (less than 5 percent by weight) are used in silicone oil formulations, then formulation stability is maintained, but the effectiveness for skin oxygenation is reduced
Solution Approach 1:
The patent changes the parameter composition of the oxygen carrier system by combining perfluorocarbon compounds with silicone polymer emulsions and oil or water bases in specific ratios. This parameter optimization allows the oxygen carrier to be used at higher concentrations (1-40% by weight in final formulation) while maintaining formulation stability, thereby improving oxygen delivery effectiveness without sacrificing stability.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The system maintains a higher oxygen concentration for an extended period, enabling prolonged oxygen delivery to skin cells, and can be used at higher concentrations in silicone oil-containing formulations without stability problems, enhancing skin oxygenation.
Implementation Method 1
a liquid perfluorinated or partially fluorinated hydrocarbon or hydrocarbon mixture with a moiety of 0.1-10 percent by weight
Implementation Method 2
oxygen gas with a partial pressure of 180 to 600 mbar is bubbled through the entire composition while stirring with 200-400 r.p.m. and at ambient temperature (18-25° C.) over a period of 15 to 100 minutes
Data Source
AI summary
The invention relates to an oxygen carrier system which is suitable for applying gaseous oxygen to the skin in cosmetic and dermatological forms of application. Said system comprises 0.1 to 10 percent by weight of a liquid perfluorinated or partially fluorinated hydrocarbon or hydrocarbon mixture, 10 to 85 percent by weight of a liquid silicone polymer or silicone polymer mixture, and 5 to 25 percent by weight of an oil base or water base, all percentages being in relation to the total weight of the carrier system. Major moieties of the inventive system can be introduced without stability problems especially into silicone oil-containing formulations.