Oxygen-Generating Dressing for Deep Skin Delivery

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Solution Overview

Problem

Current topical oxygen therapies for skin are inadequate in delivering oxygen to deeper skin layers, especially in conditions of inflammation or aging, and often require cumbersome equipment or high concentrations of peroxidic species, which can be harmful.

Innovation Solution

A dressing that generates oxygen catalytically at the skin surface under semi-occlusion, using a peroxide compound and catalyst, allowing high oxygen production for up to two hours without compressed oxygen, and featuring a self-adhesive patch with a semipermeable film to enhance penetration into deeper tissues.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If high concentrations of peroxidic species are used to deliver oxygen to deeper skin layers, then oxygen delivery effectiveness is improved, but harmful effects on skin increase

Engineering Contradiction:
Improveoxygen delivery effectivenessVSAvoidharmful effects on skin
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent changes the concentration parameter of peroxidic species from high to low (below detectable levels), while maintaining effective oxygen delivery through optimized catalyst systems and semi-occlusive delivery mechanisms. This resolves the contradiction by achieving reliable oxygen delivery without harmful high concentrations.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent introduces catalysts as intermediary substances that enable oxygen generation from peroxide compounds at low concentrations. The catalyst acts as a mediator that amplifies the oxygen-producing effect without requiring high peroxide concentrations, thus avoiding skin harm while maintaining delivery effectiveness.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Reliability

If topical oxygen therapy is applied to intact skin, then skin health and appearance are improved, but oxygen penetration to deeper layers is insufficient

Engineering Contradiction:
Improveskin health improvementVSAvoidoxygen penetration depth
Core Design Contradiction:
ReliabilityVSQuantity of substance

Solution Approach 1:

The patent employs a semi-occlusive film or dressing as a flexible barrier that enhances oxygen penetration through intact skin. The semi-occlusive nature allows controlled oxygen delivery while maintaining skin hydration and promoting deeper oxygen diffusion, resolving the contradiction between skin health improvement and penetration depth.

Inventive Principle:
Principle #30Flexible shells and thin films

Solution Approach 2:

The patent replaces mechanical compression methods with a chemical-catalytic system that generates oxygen directly at the skin surface. This substitution allows oxygen to diffuse naturally into deeper layers without mechanical force, achieving both skin health improvement and adequate penetration depth.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Duration of action of moving object

If oxygen is delivered to deeper skin layers for extended periods, then therapeutic benefits are improved, but exposure to peroxidic species increases

Engineering Contradiction:
Improvetherapeutic durationVSAvoidperoxidic species exposure
Core Design Contradiction:
Duration of action of moving objectVSObject-affected harmful factors

Solution Approach 1:

The patent employs a self-regulating catalytic system that generates oxygen only when needed and automatically ceases when the peroxide is depleted. This self-service mechanism allows extended therapeutic duration without prolonged harmful exposure, as the low concentration peroxide is rapidly converted to oxygen and water by the catalyst.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The patent converts the potentially harmful peroxidic species into beneficial oxygen through catalytic decomposition. The harmful peroxide is transformed into useful oxygen for skin therapy, with the reaction products being harmless water and oxygen, thus enabling extended treatment without accumulated harm.

Inventive Principle:
Principle #22Blessing in disguise (Convert harm into benefit)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Effectively delivers oxygen to improve skin health and appearance, treat anaerobic infections like acne, and prevent aging without prolonged exposure to harmful peroxidic species, while being suitable for intact skin and sensitive areas.

Implementation Method 1

A dressing that generates oxygen catalytically at the skin surface under semi-occlusion, using a peroxide compound and catalyst

Methodology Applied
Scientific EffectCatalysis: Catalysis

Implementation Method 2

The oxygen is absorbed transcutaneously through the outer epithelium and into the deeper dermal and subcutaneous layers

Methodology Applied
Scientific EffectDiffusion: Diffusion

Data Source

PatentUS9044462B2Method for oxygen treatment of intact skin
Publication Date: 2015.06.02 AVENT INC

AI summary

Oxygen therapy for healthy or inflamed but intact skin involves placing an oxygen-generating dressing onto the skin to be treated, the oxygen-generating bandage being a one-time use dressing capable of generating oxygen for only a short period of time, not to exceed about 4 hours.