Multimodal Oxygen Therapy Prediction From CT and Clinical Data

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Solution Overview

Problem

Predicting disease progression of COVID-19 and other infectious diseases is challenging due to the lack of definitive therapies, vaccines, and specific antiviral drugs, making it difficult to determine appropriate medical treatments such as oxygen therapy.

Innovation Solution

A deep learning framework that combines medical imaging data, specifically CT scans, with clinical metadata to train neural networks for predicting the need for oxygen therapy in patients with COVID-19, using techniques like EfficientNet-B7 for feature extraction and multi-modal deep learning to enhance prediction accuracy.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If machine learning techniques are used to predict disease progression, then prediction accuracy is improved, but computational complexity and data processing requirements increase

Engineering Contradiction:
Improveprediction accuracyVSAvoidcomputational complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The model processes medical data in segmented features rather than raw data, dividing the input into discrete numerical features that can be processed more efficiently. This segmentation approach maintains prediction accuracy while reducing computational complexity by working with pre-extracted features instead of raw medical images or unprocessed clinical data.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The system performs preliminary processing of medical data before inputting to the machine learning model, including normalization and feature extraction. This preliminary action prepares the data in advance, reducing the computational burden during the actual prediction phase while maintaining high prediction accuracy.

Inventive Principle:
Principle #10Preliminary action

2Measurement precision

If multi-modal deep learning is used to combine imaging and clinical data, then prediction accuracy is improved, but data processing time and computational resources increase

Engineering Contradiction:
Improveprediction accuracyVSAvoiddata processing time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The system transforms multi-modal medical data into normalized numerical parameters, changing the state of the data from raw heterogeneous formats to standardized numerical representations. This parameter transformation enables efficient processing of multiple data types while maintaining the predictive power of combining imaging and clinical information.

Inventive Principle:
Principle #35Parameter changes

3Reliability

If neural networks are trained with normalized input features, then model performance is improved, but preprocessing complexity increases

Engineering Contradiction:
Improvemodel performanceVSAvoidpreprocessing complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The system implements a universal normalization process that handles multiple types of medical features through a single standardized procedure. This multi-functional preprocessing approach improves model performance by ensuring consistent input quality while reducing overall complexity by using one normalization framework for all feature types rather than separate processing for each feature category.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Data Source

PatentUS12620484B2Machine-learning techniques for oxygen therapy prediction using medical imaging data and clinical metadata
Publication Date: 2026.05.05 NVIDIA CORP
  • US12620484B2 patent drawing
  • US12620484B2 patent drawing
  • US12620484B2 patent drawing

AI summary

Apparatuses, systems, and techniques to train one or more neural networks based, at least in part on, medical imaging data and clinical metadata or inference using one or more neural networks trained as such. In at least one embodiment, one or more circuits to train one or more neural network to predict a treatment for a patient suspected to have or confirmed to have COVID-19 based, at least in part on, medical imaging data and clinical metadata.