Oxygen Ventilator SpO2 Feedback Control for Stable FiO2

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Solution Overview

Problem

Existing ventilators struggle to provide safe and automated oxygen administration to patients, particularly premature infants, children, and adults, often leading to fluctuations in arterial oxygen saturation (SpO2) that can cause oxidative stress and complications like retinopathy of prematurity, requiring significant clinical intervention.

Innovation Solution

A ventilator system with a programmable control device and oxygen sensor that adjusts FiO2 levels based on real-time SpO2 measurements, displaying target and measured values graphically, allowing for automated control and reducing manual adjustments.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If manual monitoring and adjustment of oxygen levels is performed, then clinical personnel can respond to patient needs, but large fluctuations in SpO2 occur causing oxidative stress and complications

Engineering Contradiction:
ImproveSpO2 stabilityVSAvoidoxidative stress
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The ventilator continuously monitors SpO2 levels and automatically adjusts FiO2 based on real-time feedback from oxygen saturation measurements. The control unit compares measured SpO2 values with target ranges and modifies oxygen concentration accordingly, creating a closed-loop system that maintains stable SpO2 levels and prevents harmful fluctuations

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The ventilator system performs self-regulation of oxygen delivery by automatically adjusting FiO2 settings based on its own monitoring data. The device independently maintains appropriate oxygen levels without requiring continuous manual intervention, thereby ensuring stable SpO2 and preventing oxidative stress

Inventive Principle:
Principle #25Self-service

2Ease of operation

If automated SpO2-based control is implemented, then SpO2 stability improves and clinical workload decreases, but device complexity increases

Engineering Contradiction:
Improveclinical workloadVSAvoidcontrol system complexity
Core Design Contradiction:
Ease of operationVSDevice complexity

Solution Approach 1:

The ventilator integrates multiple functions including oxygen saturation monitoring, automatic FiO2 adjustment, and graphical display capabilities within a single device. The control unit performs both ventilation control and SpO2-based regulation, while the display shows multiple parameters simultaneously, reducing the need for separate monitoring equipment and simplifying overall system operation

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The system replaces manual mechanical adjustment of oxygen levels with automated electronic control. The control unit uses electronic algorithms to process SpO2 data and automatically modify FiO2 settings, eliminating the need for continuous manual intervention and reducing clinical workload despite increased internal device complexity

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Measurement precision

If frequent SpO2 measurements are taken, then real-time control accuracy improves, but measurement time and potential interference increase

Engineering Contradiction:
ImproveSpO2 control accuracyVSAvoidcontrol period duration
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The ventilator performs SpO2 measurements and FiO2 adjustments at defined control periods rather than continuously. This periodic measurement approach maintains adequate control accuracy while allowing the patient adequate time between measurements and adjustments, balancing precision with minimal interference to normal physiological processes

Inventive Principle:
Principle #19Periodic action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The system maintains stable SpO2 levels, reducing clinical workload and minimizing oxidative stress by continuously monitoring and adjusting oxygen concentration, enabling safer and more efficient ventilation.

Implementation Method 1

an oxygen sensor for determining an oxygen saturation (SpO2) of the patient

Methodology Applied
Scientific EffectAbsorption Spectroscopy: Absorption Spectroscopy

Data Source

PatentEP3650068B1Ventilation apparatus for ventilation with oxygen
Publication Date: 2025.08.13 LOWENSTEIN MEDICAL TECH SA
  • EP3650068B1 patent drawingFigure 1
  • EP3650068B1 patent drawingFigure 2
  • EP3650068B1 patent drawingFigure 3

AI summary

A ventilator for ventilating a patient with FiO2 preset values, comprising a control unit, a respiratory gas source, an oxygen source, a display (3) and operating elements (2) and at least one interface (8, 18, 28) via which an SpO2 sensor is connected to the ventilator for determining the patient's oxygen saturation, wherein the control unit controls the respiratory gas source and the oxygen source to specify a defined FiO2, wherein target values ​​for SpO2 and/or FiO2 can be specified via the operating elements (2) or an interface, characterized in that the control unit displays current measured values ​​and/or target values ​​for SpO2 on the display and displays current measured values ​​and/or preset values ​​for FiO2 on the display.