Parallel-accelerated Complex Subtraction MRI Background Suppression

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Solution Overview

Problem

Current MRI techniques face challenges in effectively suppressing unwanted background signal, particularly in accelerated MR imaging, where artifacts from patient motion and 'g-factor' noise significantly degrade diagnostic quality.

Innovation Solution

A method involving complex subtraction of MR data sets in k-space is employed, where a first and second set of undersampled k-space data are acquired under different conditions, and then subtracted to produce a differential k-space data set, which is reconstructed to suppress background signal, reducing artifacts and noise amplification.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Speed

If parallel imaging techniques are used to accelerate data acquisition, then scanning speed is improved, but image quality deteriorates due to noise amplification and artifacts

Engineering Contradiction:
Improvescanning speedVSAvoidimage quality
Core Design Contradiction:
SpeedVSManufacturing precision

Solution Approach 1:

The patent applies preliminary action by performing background suppression through complex subtraction in k-space before the parallel imaging reconstruction process. By pre-processing the k-space data to remove background signals and reduce artifacts, the subsequent parallel imaging reconstruction operates on cleaner data, thereby maintaining image quality while achieving acceleration through techniques like GRAPPA

Inventive Principle:
Principle #10Preliminary action

2Object-generated harmful factors

If background suppression is performed in image space, then background signal is reduced, but motion artifacts and noise are amplified

Engineering Contradiction:
Improvebackground signalVSAvoidmotion artifacts and noise
Core Design Contradiction:
Object-generated harmful factorsVSObject-affected harmful factors

Solution Approach 1:

The patent applies dimensionality change by performing background suppression in k-space (frequency domain) rather than in image space (spatial domain). This dimensional transformation allows the complex subtraction operation to effectively remove background signals while avoiding the amplification of motion artifacts and noise that occurs when subtraction is performed in the image domain. The k-space operation distributes noise evenly across the image, preventing localized artifact amplification

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach results in background-suppressed MR images with reduced artifacts and improved image quality by distributing noise evenly across the image, reducing the prevalence and conspicuity of motion artifacts and enhancing the accuracy of parallel imaging techniques like GRAPPA.

Implementation Method 1

A method for producing background-suppressed magnetic resonance (MR) images via complex subtraction of magnetic resonance (MR) data sets in k-space

Methodology Applied
Scientific EffectComplex subtraction:

Data Source

PatentUS8274284B2Parallel-accelerated complex subtraction MRI
Publication Date: 2012.09.25 NORTHSHORE UNIV HEALTHSYST
  • US8274284B2 patent drawing
  • US8274284B2 patent drawing
  • US8274284B2 patent drawing

AI summary

A method for producing background-suppressed MR images with improved resistance to subject motion and noise, particularly that associated with parallel imaging techniques. An MRI system is employed to acquire two sets of undersampled k-space data under different scan conditions. A differential k-space data set is then formed by complex, pairwise subtraction of the two undersampled k-space data sets and a background-suppressed MR is reconstructed from the differential k-space data set using an accelerated reconstruction technique, such as GRAPPA.