Parallel Blood Component Processing Circuit
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Solution Overview
Problem
Current blood processing systems require multiple sequential therapies for different blood components, which are time-consuming and inefficient, often necessitating multiple disposable circuits and needle insertions, and do not allow for simultaneous treatment of multiple components.
Innovation Solution
A disposable kit with a fluid circuit comprising multiple pathways that enables simultaneous separation and treatment of blood components, allowing for concurrent processing of plasma and red blood cells within the same circuit, using centrifugation or spinning membranes, with separate and independent pathways to maintain component isolation during treatment.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If multiple sequential therapies are used for different blood components, then each component can be treated thoroughly, but the treatment time increases and processing efficiency decreases
Solution Approach 1:
The blood processing system is divided into multiple independent processing pathways, each dedicated to treating a specific blood component (e.g., plasma pathway, RBC pathway, platelet pathway). This segmentation allows simultaneous treatment of different components without interference, resolving the contradiction by enabling parallel processing that maintains treatment effectiveness while reducing total treatment time.
Solution Approach 2:
Multiple treatment pathways that were previously sequential are merged into a single integrated system that processes multiple blood components simultaneously. The system combines separate treatment lines for plasma, red blood cells, and platelets into one coordinated apparatus, allowing concurrent therapies while maintaining the reliability of each individual treatment protocol.
2Reliability
If multiple sequential therapies are performed, then comprehensive treatment is achieved, but the number of disposable circuits and needle insertions increases
Solution Approach 1:
The blood processing system is designed as a universal platform that can handle multiple blood components through a single integrated circuit system. The apparatus incorporates multi-functional modules that can process plasma, red blood cells, and platelets simultaneously using shared infrastructure (pumps, tubing, control systems), thereby reducing the number of separate disposable circuits needed while maintaining comprehensive treatment capability.
Solution Approach 2:
Multiple treatment pathways are merged into a single integrated circuit system with shared components. The system combines separate treatment lines for different blood components into one coordinated apparatus with common pumps, valves, and control mechanisms, reducing device complexity while achieving comprehensive treatment of all necessary blood components.
3Manufacturing precision
If blood components are processed sequentially, then each component receives dedicated attention, but processing efficiency and productivity decrease
Solution Approach 1:
The processing system is segmented into dedicated pathways for different blood components, with each pathway optimized for its specific treatment requirements. This segmentation ensures that each component receives focused, high-quality processing while the overall system operates in parallel, thereby maintaining manufacturing precision while significantly improving productivity through simultaneous multi-component treatment.
4Reliability
If separate processing systems are used for different blood components, then component isolation is maintained, but the overall system complexity and number of kits required increases
Solution Approach 1:
The system uses segmented, dedicated pathways for each blood component that physically separate components throughout the processing journey. Each pathway includes isolated pumps, tubing, and treatment modules specific to its component, ensuring reliable component isolation while using a shared control system and common interface to manage overall system operations, thereby reducing kit complexity.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This approach reduces treatment time, decreases the number of disposable kits and needle insertions, and enables simultaneous therapy for multiple blood components, improving efficiency and reducing the complexity of blood processing procedures.
Implementation Method 1
The separation device may be configured to separate the blood into two or more components
Data Source
AI summary
A kit for blood component processing comprising a fluid circuit into which blood is drawn, wherein the fluid circuit comprises a plurality of pathways; wherein the first pathway is configured to receive blood drawn from a blood source and leads to a separation device, wherein the separation device is configured to separate the blood into components; wherein the second pathway is configured to receive a first component from the separation device and transport at least a portion of the first component to a first processing device, wherein the first processing device may alter the first component to produce a first output; and wherein the third pathway is configured to receive a second component from the separation device and transport at least a portion of the second component to a second processing device, wherein the second processing device may alter the second component to produce a second output.