Parallel Drug Reservoir and Dosing Unit for Compact Injection Device

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Solution Overview

Problem

Hand-held injection devices for self-administration of liquid drugs, such as insulin, face challenges in achieving discreetness due to their length and complexity, particularly when used in public settings, and existing designs do not adequately address the need for compactness and precise dosing.

Innovation Solution

The design incorporates an elongated drug reservoir and dosing unit arranged in parallel, with a metering cavity and valve arrangement that allows for stepwise discharge of the drug, enabling a more compact form factor and improved dosing precision by decoupling the dosing unit from the drug reservoir, allowing for higher concentration insulin formulations and reduced overall size.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Length of moving object

If the drug reservoir and dosing unit are arranged in parallel, then the device length is reduced and discreetness is improved, but the structural complexity increases

Engineering Contradiction:
Improvedevice lengthVSAvoidstructural complexity
Core Design Contradiction:
Length of moving objectVSDevice complexity

Solution Approach 1:

The device is divided into separate functional modules: a drug reservoir module and a dosing unit module, which can be arranged in parallel or series configurations. This segmentation allows the long drug reservoir to be positioned separately from the dosing mechanism, reducing the overall device length while maintaining functional integrity.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent transitions from a traditional linear (one-dimensional) arrangement of components to a two-dimensional parallel arrangement. The drug reservoir and dosing unit are positioned side-by-side rather than end-to-end, effectively utilizing spatial dimensions to reduce device length without proportionally increasing complexity.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

2Measurement precision

If the dosing unit is decoupled from the drug reservoir, then dosing precision is improved and higher concentration formulations are enabled, but the device complexity increases

Engineering Contradiction:
Improvedosing precisionVSAvoiddevice complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The dosing unit is extracted and separated from the drug reservoir, creating an independent dosing module. This allows the dosing mechanism to be optimized for precision without being constrained by reservoir design, enabling accurate metering of high-concentration formulations while the reservoir can be independently optimized for drug storage.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

A coupling mechanism or interface is introduced as an intermediary between the drug reservoir and dosing unit. This intermediary enables precise fluid transfer and metering while allowing the two modules to be independently designed and optimized, managing the complexity through modular connection rather than integrated design.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Volume of moving object

If the device is designed for compact form factor, then discreetness and user convenience are improved, but the drug reservoir size is reduced

Engineering Contradiction:
Improvedevice volumeVSAvoiddrug reservoir capacity
Core Design Contradiction:
Volume of moving objectVSQuantity of substance

Solution Approach 1:

The dosing unit is designed to nest within or around the drug reservoir structure, or components are arranged in a nested configuration. This allows the device to maintain a compact external volume while accommodating both the drug reservoir and dosing mechanisms, preserving discreetness without proportionally reducing drug capacity.

Inventive Principle:
Principle #7Nested doll (Nesting)

Data Source

PatentEP2753380B1Hand-held injection device and disposable module
Publication Date: 2020.05.06 F HOFFMANN LA ROCHE & CO AG
  • EP2753380B1 patent drawingFigure 1
  • EP2753380B1 patent drawingFigure 2a
  • EP2753380B1 patent drawingFigure 2b

AI summary

Disclosed is a hand-held injection device (1) for the metered injection of a liquid drug into a person's tissue, the injection device including: . a) an elongated drug reservoir (100), the drug reservoir having a longitudinal reservoir axis (A), . b) an elongated dosing unit (200), the dosing unit (200) having a dosing unit inlet, a dosing unit outlet, and a metering cavity (207), the dosing unit (200) having a longitudinal dosing unit axis (Alpha'), the drug reservoir (100) being fluidically coupled to the dosing unit inlet (215a), . . the dosing unit (200) and the drug reservoir (100) being arranged such that the longitudinal dosing unit axis (Alpha') is in parallel alignment with the reservoir axis (A).