Parallel Labware Movers for Flexible Laboratory Automation
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Solution Overview
Problem
Current laboratory automation systems lack flexibility and modularity, requiring rigid process definitions and relying on complex orchestration, which hinders user productivity and ease of use, especially in dynamic scientific processes.
Innovation Solution
A flexible parallelized laboratory automation system with programmable movers and tools that allow independent operation on multiple axes, enabled by a parallel control system, allowing users to define actions and sequences dynamically, minimizing collisions and optimizing motion paths for efficient labware movement.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Adaptability or versatility
If traditional fixed pipettes move in unison along X, Y, and Z axes, then the system structure is simple, but the flexibility and adaptability for different pipetting protocols is limited
Solution Approach 1:
The system divides the pipetting function into independent modular units (individual pipettes or channel heads) that can operate autonomously. Each pipette or channel head is a separate controllable entity rather than a fixed rigid structure, allowing flexible configuration for different protocols while maintaining manageable system complexity through standardization of modular components.
Solution Approach 2:
The system transitions from fixed rigid motion to dynamic programmable motion. Independent pipettes or channel heads can move autonomously along multiple axes with programmable paths, speeds, and coordinates. This dynamic capability enables adaptation to various pipetting protocols while the underlying modular architecture keeps system complexity manageable.
2Adaptability or versatility
If multiple independent pipettes are used to pipette different volumes at different heights and positions, then the adaptability increases, but the device complexity and coordination requirements increase
Solution Approach 1:
Independent pipettes or channel heads are designed as universal modules capable of performing multiple functions (different volumes, heights, positions, aspiration and dispensing) through programmable control. This multi-functionality reduces the need for specialized equipment for each task while keeping individual module complexity manageable through standardization.
Solution Approach 2:
Each independent pipette or channel head operates autonomously with its own motors and control systems, making self-service decisions about positioning and operation based on programmed instructions. This autonomy reduces the coordination complexity that would arise from centralized control of all movements.
3Productivity
If 96-channel or 384-channel heads are used for unison pipetting, then the productivity increases, but the flexibility for independent operation of individual channels is reduced
Solution Approach 1:
The system offers channel heads that can operate in both unified and segmented modes. While the physical structure may be a 96-channel or 384-channel head for high-throughput unison pipetting, the control system segments each channel into an independently controllable unit, enabling selective operation of individual channels or subsets when protocol flexibility is required.
Solution Approach 2:
The channel head system transitions from static unison operation to dynamic selective operation. The system can dynamically switch between operating all channels together for high productivity and operating individual channels independently for protocol flexibility, with programmable control adjusting the operational mode based on task requirements.
4Productivity
If labware motion in horizontal axes is automated with complex gear systems, then the productivity and precision improve, but the device complexity and potential collision risks increase
Solution Approach 1:
The system replaces complex mechanical gear systems with direct-drive motor systems or simplified mechanical transmissions. Independent motors on each mover provide precise horizontal axis control without requiring complex gear mechanisms, reducing mechanical complexity while maintaining productivity and precision through electronic control.
Solution Approach 2:
Each mover is equipped with its own independent motor and control system, making autonomous navigation decisions to reach target positions without requiring complex centralized mechanical coordination. This self-service capability reduces mechanical complexity while enabling efficient parallel operation of multiple movers.
Data Source
AI summary
A system and method for a flexible parallelized system for laboratory automation using labware movement. The parallel laboratory system includes a plurality of independent tools and a plurality of movers. The plurality of movers includes at least one labware item. The plurality of movers is configured to freely operate on a first surface of the parallel laboratory system in a first direction and in a second direction. The plurality of independent tools is configured to independently operate in a third direction. The plurality of independent tools and plurality of movers are controlled by a parallel automation control system. The parallel automation control system includes a controller, a lab automation device, and a user interface. The parallel automation control system commands the plurality of tools and movers to operate in a parallel automation process. An apparatus having the plurality of independent tools, the plurality of movers, and the parallel automation control system is also included.