Parallel Line Biochip Segmentation for Multiplex Allergen Detection
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Conventional line strip biochips are inefficient in analyzing multiple elements simultaneously due to their length, requiring large specimen amounts and repetitive process cycles, and are limited in detecting various allergens at once.
Innovation Solution
A parallel line biochip with multiple line strips disposed in parallel, using a membrane support such as nitrocellulose or PVDF, allows for the simultaneous analysis of multiple markers by minimizing individual line strips and optimizing their horizontal length for efficient detection.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Adaptability or versatility
If many marker lines are put on a single long strip, then the number of detectable elements increases, but the strip becomes too long to perform tests effectively and processing time increases
Solution Approach 1:
The patent divides the single long strip into multiple separate line strips, each containing a subset of marker lines. This segmentation allows the markers to be distributed across multiple shorter strips rather than one long strip, improving testability while maintaining the ability to detect multiple elements simultaneously.
Solution Approach 2:
The patent transitions from a single-dimensional long strip layout to a multi-dimensional arrangement where multiple line strips are positioned side by side. This dimensional change allows the system to accommodate more marker lines without increasing the length of individual strips, as the strips are arranged in parallel across a broader area.
2Adaptability or versatility
If many marker lines are put on a single long strip, then the number of detectable elements increases, but the processing time and specimen amount required increase
Solution Approach 1:
By segmenting the markers into multiple separate line strips, the patent enables parallel processing of multiple elements simultaneously. Each line strip can be processed independently, and the results can be read in parallel, significantly reducing the total processing time compared to a single long strip that would require sequential processing.
Solution Approach 2:
The patent maintains continuous useful action by allowing multiple detection reactions to occur simultaneously across different line strips. The test sample can interact with all markers across all strips at the same time, and the detection process can proceed in parallel, ensuring continuous productive operation without idle time.
3Adaptability or versatility
If many marker lines are put on a single long strip, then the number of detectable elements increases, but the specimen amount required increases
Solution Approach 1:
The patent segments the detection targets into multiple separate line strips, each requiring a portion of the total specimen. By distributing the markers across multiple strips, the system can use the same total specimen amount more efficiently, as each strip processes a subset of markers in parallel rather than requiring the full specimen amount for each individual marker.
Solution Approach 2:
The patent arranges multiple line strips side by side in a spatial dimension, allowing the specimen to be distributed across multiple parallel detection paths. This dimensional arrangement enables simultaneous detection of multiple elements using a divided specimen amount, improving detection capacity without proportionally increasing the total specimen required.
4Ease of manufacture
If a single long strip is used, then manufacturing is simpler, but the ability to analyze various elements simultaneously is limited
Solution Approach 1:
The patent segments the single long strip into multiple separate line strips, each containing a subset of markers. This segmentation maintains the simplicity of individual strip manufacturing while enabling simultaneous analysis of multiple elements through parallel processing across the multiple strips.
Solution Approach 2:
The patent combines multiple separate line strips into a single integrated biochip structure that can be manufactured as one unit. This merging approach preserves the manufacturing simplicity of individual strips while enabling simultaneous multi-element analysis through the combined parallel structure of multiple strips.
Data Source
AI summary
The present invention is related to a parallel line biochip for multiplex diagnosis. The parallel line biochip for multiplex diagnosis includes a plurality of line strips disposed in parallel, and a well configured to immobilize the line strips. Since the parallel line biochip for multiplex diagnosis can be used to connect two or more line strips in parallel, the parallel line biochip for multiplex diagnosis has an effect of measuring various materials present in a biological test sample at the same time.