Parallel Pore Template for Mass-Produced Functional Microparticles

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Solution Overview

Problem

Current methods for fabricating functional microparticles, such as fuel cells, are not scalable or efficient in producing devices with specific functionalities like electrical current generation, therapeutic payload delivery, or magnetic manipulation, especially for implantation in biological systems.

Innovation Solution

A scalable, massively parallel process using a parallel pore working piece, like an anodized aluminum oxide filter membrane, to synthesize microparticles with defined, uniform pores, enabling the simultaneous production of billions of functional microparticles with integrated anodes, cathodes, and magnetic components, capable of oxidizing biofuels and reducing oxygen, and incorporating therapeutic payloads.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If conventional fabrication methods are used, then manufacturing complexity is reduced, but productivity and scalability are insufficient for mass production of functional microparticles

Engineering Contradiction:
Improveproduction rate of functional microparticlesVSAvoidfabrication process complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The fabrication process is segmented into distinct stages: forming uniform pores in a template substrate, depositing functional materials (anode, cathode, separator) into individual pores, and releasing particles. This segmentation enables parallel processing where billions of pores are treated simultaneously, dramatically increasing productivity while maintaining controlled complexity at each stage

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The invention uses a template substrate with uniformly distributed pores as a master copy that replicates the functional microparticle structure across billions of locations. Each pore serves as a mold that copies the same functional architecture (anode-cathode-separator configuration), enabling mass production with consistent functionality without requiring complex individual fabrication for each particle

Inventive Principle:
Principle #26Copying

2Productivity

If scalable production is implemented using parallel pore structures, then productivity increases, but manufacturing precision requirements increase

Engineering Contradiction:
Improvemass production capabilityVSAvoidpore uniformity and functional layer deposition precision
Core Design Contradiction:
ProductivityVSManufacturing precision

Solution Approach 1:

The template substrate provides locally uniform pores with precisely controlled dimensions and spacing. Each pore maintains identical geometric properties (diameter, depth, shape) ensuring that functional materials deposited within each pore achieve consistent thickness and distribution. This local quality control enables mass production while maintaining high manufacturing precision for each individual particle

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

The template substrate is pre-formed with uniformly distributed pores before any functional materials are deposited. This preliminary action establishes the precise geometric framework that guides subsequent material deposition, ensuring that anodes, cathodes, and separators are positioned with high precision across all billions of particles simultaneously, rather than requiring precision alignment during the deposition process itself

Inventive Principle:
Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This method allows for the efficient and scalable production of functional microparticles that can be implanted in biological systems, effectively generating electrical energy, delivering therapeutic payloads, and manipulating magnetic fields, addressing the limitations of existing fabrication techniques.

Implementation Method 1

electrodeposition of a conductive layer into pores of the parallel pore working piece

Methodology Applied
Scientific EffectElectrodeposition: Electrodeposition

Implementation Method 2

a separator membrane material that allows the passage of a fuel substrate (e.g., glucose) but inhibits the passage of oxygen molecules

Methodology Applied
Scientific EffectSelective permeability: Semipermeable Membrane

Implementation Method 3

anodized aluminum oxide filter membrane

Methodology Applied
Scientific EffectAnodizing: Anodising

Data Source

PatentUS10985383B2Scalable, massively parallel process for making micro-scale functional particles
Publication Date: 2021.04.20 WEINBERG MEDICAL PHYSICS INC
  • US10985383B2 patent drawing
  • US10985383B2 patent drawing
  • US10985383B2 patent drawing

AI summary

A method of fabrication produces one or more functional microparticles using a parallel pore working piece. In one embodiment, the method forms a particle that includes a segment for the oxidation of a biofuel (such as glucose) and the reduction of oxygen. The particle may be synthesized in a structure with defined and parallel, uniform, thin pores that completely penetrate the structure. Further, the functional microparticle may be configured to reside in a human or animal body or cell such that it may be self-contained fuel cell having an anode, a cathode, a separator membrane, and a magnetic component. In other embodiments, the functional microparticles may deliver energy or therapeutic materials in the body.