Parallel Transmission Pulse Design for SAR Hotspot Mitigation

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Solution Overview

Problem

Simultaneous multislice imaging at high magnetic field strengths faces challenges with peak RF power exceeding amplifier limits and local SAR hotspots, necessitating efficient methods to optimize RF and gradient waveforms while maintaining flip angle homogeneity and reducing pulse duration.

Innovation Solution

The method employs the IMPULSE pTx optimization algorithm to determine spoke locations and channel weights for minimizing SAR hotspots and peak pulse power, combined with a time-optimal VERSE algorithm to enforce peak power constraints, reshaping RF and gradient waveforms without altering the excitation profile.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If simultaneous multislice imaging is performed at ultra-high field strengths, then image quality and signal-to-noise ratio are improved, but peak RF power exceeds amplifier limits and local SAR hotspots occur

Engineering Contradiction:
Improveimage qualityVSAvoidpeak RF power
Core Design Contradiction:
Measurement precisionVSPower

Solution Approach 1:

The patent applies segmentation by dividing the simultaneous multislice excitation into multiple individually optimized subpulses, each targeting specific slices with controlled RF power. The IMPULSE algorithm optimizes each subpulse separately to minimize peak power while maintaining excitation accuracy, and the VERSE algorithm further segments the power envelope to enforce peak power constraints without altering the excitation profile.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent employs parameter changes by optimizing the RF and gradient waveform parameters through the IMPULSE algorithm, which adjusts amplitude and phase parameters of subpulses. The VERSE algorithm then modifies the temporal parameter (pulse duration) by rescaling the RF and gradient waveforms to enforce peak power constraints while preserving the excitation profile characteristics.

Inventive Principle:
Principle #35Parameter changes

2Measurement precision

If simultaneous multislice imaging is performed at ultra-high field strengths, then image quality is improved, but local SAR hotspots occur due to B1+ inhomogeneity

Engineering Contradiction:
Improveimage qualityVSAvoidlocal SAR hotspots
Core Design Contradiction:
Measurement precisionVSObject-affected harmful factors

Solution Approach 1:

The patent applies local quality by using parallel transmission with multiple independently controlled RF channels, each with optimized amplitude and phase parameters. The IMPULSE algorithm determines channel-specific weights to create localized B1+ field distributions that achieve uniform flip angles across slices while minimizing SAR hotspots in specific regions. The VERSE algorithm further refines local power distribution by rescaling waveforms.

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

The patent employs feedback mechanisms through the IMPULSE optimization algorithm, which iteratively adjusts RF and gradient waveform parameters based on calculated excitation accuracy and SAR constraints. The algorithm uses feedback from Bloch equation simulations to refine subpulse parameters, ensuring that SAR hotspots are suppressed while maintaining the desired excitation profile.

Inventive Principle:
Principle #23Feedback

3Quantity of substance

If multiple subpulses are summed for simultaneous multislice excitation, then slice coverage is increased, but peak RF power exceeds amplifier limits

Engineering Contradiction:
Improveslice coverageVSAvoidpeak RF power
Core Design Contradiction:
Quantity of substanceVSPower

Solution Approach 1:

The patent applies preliminary action by pre-optimizing the RF and gradient waveforms using the IMPULSE algorithm before actual simultaneous multislice excitation. The algorithm calculates optimal subpulse parameters in advance, and the VERSE algorithm pre-scales the waveforms to ensure peak power constraints are met. This preliminary optimization prevents peak power violations during the actual multi-slice excitation while maintaining comprehensive slice coverage.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent employs dynamics by using time-varying RF and gradient waveforms with optimized temporal profiles. The IMPULSE algorithm generates dynamic subpulse sequences with varying amplitudes and phases, and the VERSE algorithm dynamically rescales the waveforms in time to enforce peak power constraints. This dynamic approach allows flexible adjustment of power distribution across time to accommodate multiple slices within amplifier limits.

Inventive Principle:
Principle #15Dynamics

4Object-affected harmful factors

If RF and gradient waveforms are optimized for SAR reduction, then local SAR hotspots are mitigated, but pulse duration increases

Engineering Contradiction:
Improvelocal SAR hotspotsVSAvoidpulse duration
Core Design Contradiction:
Object-affected harmful factorsVSDuration of action of moving object

Solution Approach 1:

The patent applies parameter changes by using the VERSE algorithm to optimally rescale the RF and gradient waveforms in the time domain. Instead of uniformly stretching the pulse, the VERSE algorithm selectively adjusts temporal parameters to minimize pulse duration while satisfying peak power constraints. This parameter optimization achieves SAR reduction without excessive pulse duration extension.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent employs partial action by applying SAR mitigation and peak power constraint enforcement only where and when necessary through the VERSE algorithm. The rescaling is applied selectively to portions of the waveform that exceed power constraints, rather than uniformly extending the entire pulse duration. This partial approach minimizes the overall pulse duration increase while still achieving the required SAR and power constraints.

Inventive Principle:
Principle #16Partial or excessive action

Data Source

PatentUS10641855B2Methods for mitigating local SAR hotspots and flip angle uniformity in ultra-high field simultaneous multislice imaging using parallel transmission
Publication Date: 2020.05.05 THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIV
  • US10641855B2 patent drawing
  • US10641855B2 patent drawing
  • US10641855B2 patent drawing

AI summary

Obtaining minimum duration parallel transmit pulses for simultaneous multislice imaging that includes minimizing specific absorption rate hotspots, using an IMPULSE pTx optimization method to determine multiple spoke locations and multiple channel weights for multiple slices while enforcing a specified flip angle inhomogeneity tolerance over the multiple slices when excited, applying a control algorithm to conform a simultaneous multislice (SMS) pulse to the excited multiple slices to minimize a cost function having terms corresponding to an excitation accuracy and a pulse power, where a regularization term in the cost function is configured by the control algorithm for excitation accuracy while limiting a peak pulse power, and applying a time-optimal variable rate selective excitation (VERSE) to enforce a peak power constraint with a minimum pulse duration by reshaping a RF waveform and a gradient waveform without altering an excitation profile if the peak power limit on a channel is exceeded.