Partial Volume Intraocular Lens Capsular Bag Segmentation
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Solution Overview
Problem
Existing intraocular lens implants suffer from increased rates of dysphotopsias and secondary cataract formation due to their small size and high refractive index, and they lose elasticity within 10 years, impairing accommodation for near vision.
Innovation Solution
A one-part intraocular lens implant made from transparent non-cellular structural material, placed in the posterior portion of the capsular bag, which does not exceed 40% of the native lens volume, allowing the anterior portion to regenerate and maintaining the flexibility of the lens capsule by avoiding artificial material in the anterior portion, combined with a capsular filling composition that promotes cellular regeneration.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Object-affected harmful factors
If small size lens implants are used, then the risk of infection is lowered and the incision size is reduced, but the rate of dysphotopsias increases due to light reflections on the retina
Solution Approach 1:
The patent applies partial action by using a reduced-volume lens implant (at most 40% of native lens volume) that occupies only the posterior portion of the capsular bag, rather than filling the entire space. This partial placement reduces the implant's interaction with incoming light paths, thereby decreasing dysphotopsias while still providing sufficient optical correction and maintaining infection risk reduction benefits.
2Ease of operation
If flexible artificial materials with high refractive index are used, then the lens implant can be introduced through small incisions, but the rate of dysphotopsias increases due to light reflections
Solution Approach 1:
The patent uses a lens implant with volume at most 40% of the native lens that is introduced through small incisions using flexible materials, but limits its placement to the posterior portion only. This partial placement reduces the surface area interacting with light, thereby minimizing reflections and dysphotopsias while maintaining the surgical advantage of small incision introduction.
3Reliability
If full size lens implants are used to create intracapsular pressure, then accommodation capability is maintained initially, but the lens capsule loses elasticity within 10 years and accommodation is lost
Solution Approach 1:
The patent uses a lens implant with volume at most 40% of the native lens that is placed only in the posterior portion of the capsular bag. This partial placement creates sufficient intracapsular pressure to support initial accommodation while leaving the anterior portion empty, which prevents the capsule from losing elasticity and maintains long-term accommodation capability.
Solution Approach 2:
The patent segments the capsular bag into anterior and posterior portions, placing the lens implant only in the posterior portion. This segmentation allows the anterior portion to remain free of artificial material, preserving capsule elasticity and enabling long-term accommodation while the posterior implant provides necessary optical function and pressure.
4Strength
If artificial materials are placed in the anterior portion, then structural support is provided, but cellular regeneration is prevented and secondary cataract forms
Solution Approach 1:
The patent extracts the lens implant from the anterior portion of the capsular bag, placing it only in the posterior portion. This extraction of artificial material from the anterior region allows cellular regeneration to occur freely in that space, preventing secondary cataract formation while the posterior implant provides necessary structural and optical support.
Solution Approach 2:
The patent provides structural support through a lens implant that occupies only the posterior portion (at most 40% of native lens volume), rather than filling the entire capsular bag. This partial placement is sufficient for maintaining capsular shape and optical function while leaving the anterior portion available for cellular regeneration, preventing secondary cataract.
Data Source
AI summary
The invention concerns an intraocular lens implant for placement into an intracapsular space of a lens capsule of an eye and a composition, kit and methods related to the lens implant. The lens implant is designed for a placement into a posterior portion of the intracapsular space after removal of a native lens body and has a convex posterior surface. The lens implant is formed of one part and is manufactured from a suitable transparent non-structural cellular material. This keeps an anterior portion of the intracapsular space free of the implant which is dimensioned to comprise at most 40% of a volume of the native lens body.