Particle Analyzer Temperature Correction
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Solution Overview
Problem
Temperature fluctuations in sample liquids affect light intensity measurements in particle analyzers, requiring strict temperature control, which is cumbersome and inefficient.
Innovation Solution
Incorporating a temperature sensor to detect and correct for temperature changes in the particles-containing liquid, allowing for real-time adjustment of analysis results without the need for strict temperature management.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If strict temperature control is implemented using an incubator, then measurement accuracy is maintained, but device complexity and operational burden increase
Solution Approach 1:
The patent extracts the temperature sensor function from the complex incubator system and places it directly in the sheath flow cell. This allows temperature detection at the measurement location without requiring a full temperature control system, thereby reducing device complexity while maintaining measurement accuracy through software-based correction.
Solution Approach 2:
The patent implements a feedback mechanism where the temperature sensor continuously monitors the sample liquid temperature, and the controlling section uses this information to correct light intensity measurements in real-time. This feedback loop eliminates the need for strict temperature control while maintaining measurement accuracy.
2Measurement precision
If strict temperature control is implemented using an incubator, then measurement accuracy is maintained, but ease of operation deteriorates
Solution Approach 1:
The system performs self-correction by automatically compensating for temperature effects on light intensity measurements. The temperature sensor and controlling section work together to adjust measurements based on actual temperature conditions, eliminating the need for manual temperature management by the operator.
Solution Approach 2:
The real-time temperature monitoring and automatic correction system provides continuous feedback to maintain measurement accuracy without requiring operator intervention for temperature control, significantly improving ease of operation.
3Ease of operation
If temperature correction is performed using a temperature sensor, then ease of operation improves, but measurement precision may deteriorate without proper correction
Solution Approach 1:
The controlling section uses temperature sensor data to dynamically correct light intensity measurements, ensuring measurement precision is maintained while allowing operational simplicity. The correction algorithm compensates for temperature-induced variations in light scattering and fluorescence intensity.
Solution Approach 2:
The system changes the measurement parameters by adjusting light intensity values based on temperature conditions. The controlling section applies correction factors derived from temperature data to maintain accurate particle analysis across varying temperature conditions.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Enables precise particle analysis without the need for constant temperature control, improving measurement accuracy and operational efficiency by accounting for temperature variations in real-time.
Implementation Method 1
a temperature sensor for detecting the temperature, of the particles-containing liquid
Implementation Method 2
a photo-detector for detecting optical information from particles in the particles-containing liquid and then converting it into an electric signal
Data Source
AI summary
Particle analyzers are described that include a cell for receiving a particles-containing liquid; a light source for irradiating light onto the particles-containing liquid; a photo-detector for detecting optical information from particles in the particles-containing liquid and converting the optical information into an electric signal; a temperature sensor for detecting a temperature of the particles-containing liquid; and a signal processing section for calculating an analysis result of the particles on the basis of an output of the photo-detector and an output of the temperature sensor. Particle analysis methods are also described.