Particle Irradiation Control Parameter Optimization

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Solution Overview

Problem

Current particle irradiation systems face challenges in accurately delivering dose distributions due to positioning inaccuracies, leading to clinically unacceptable outcomes, as small displacements can significantly impact the dose distribution during treatment.

Innovation Solution

A device and method for determining control parameters that adjust particle number distributions based on predefined dose distributions and variables accounting for differences between sampling points, optimizing the particle number distribution to ensure robust treatment plans and reduced treatment duration by using a cost function that balances dose distribution and particle dynamics.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If conventional particle irradiation systems are used with standard control parameters, then the irradiation can be performed, but positioning inaccuracies lead to clinically unacceptable dose distributions

Engineering Contradiction:
Improverobustness against positioning inaccuraciesVSAvoiddose distribution accuracy
Core Design Contradiction:
ReliabilityVSManufacturing precision

Solution Approach 1:

The method performs preliminary optimization of particle numbers at sampling points before irradiation by determining a particle number distribution that accounts for differences between sampling points. This pre-calculation creates a robust treatment plan that compensates for potential positioning inaccuracies before the actual irradiation occurs, ensuring dose distribution accuracy even when positioning errors are present.

Inventive Principle:
Principle #10Preliminary action

2Manufacturing precision

If particle numbers are optimized for each sampling point to achieve precise dose distribution, then dose accuracy improves, but treatment duration increases

Engineering Contradiction:
Improvedose distribution accuracyVSAvoidtreatment duration
Core Design Contradiction:
Manufacturing precisionVSLoss of time

Solution Approach 1:

The method optimizes parameters by determining particle numbers at sampling points using a systematic approach that balances dose distribution accuracy with treatment efficiency. The optimization considers the difference between particle numbers at different sampling points and determines an optimal distribution that achieves clinically acceptable dose distributions while reducing overall treatment duration compared to conventional methods.

Inventive Principle:
Principle #35Parameter changes

3Productivity

If conventional control parameters are used without optimization, then treatment can proceed quickly, but positioning errors cause clinically unacceptable outcomes

Engineering Contradiction:
Improvetreatment efficiencyVSAvoidrobustness against positioning inaccuracies
Core Design Contradiction:
ProductivityVSReliability

Solution Approach 1:

The system performs self-optimization by automatically determining the optimal particle number distribution at sampling points based on the treatment plan and positioning data. The method calculates the difference between particle numbers at different sampling points and adjusts the distribution accordingly, enabling the system to adapt to positioning inaccuracies without requiring manual intervention, thus maintaining both efficiency and reliability.

Inventive Principle:
Principle #25Self-service

Data Source

PatentUS8530864B2Optimization of control parameters for a particle irradiation system
Publication Date: 2013.09.10 VARIAN MEDICAL SYST PARTICLE THERAPY GMBH & CO KG
  • US8530864B2 patent drawing
  • US8530864B2 patent drawing
  • US8530864B2 patent drawing

AI summary

A device for determining control parameters for a particle irradiation system that deposits different dose values at different target points in a target volume through the selection of sampling points by a particle beam is provided. The device includes an input for receiving information relating to a predefined dose distribution via target points, and a determination component for determining a particle number distribution that is to be deposited during the irradiation via sampling points. The determining takes place using the predefined dose distribution and a variable, which takes into account differences in the particle number distribution between particle numbers of different sampling points.