Particle-Selective Agent Delivery Receiver for Clog Prevention
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Solution Overview
Problem
Existing agent delivery systems face challenges in controlling the delivery rate and particulate size of therapeutic agents, leading to clogging and inconsistent dosing, especially in deep gastrointestinal procedures.
Innovation Solution
A medical device with a receiver having multiple lumens of varying cross-sectional dimensions is used to control the delivery of therapeutic agents based on particle size, including a funnel-like interface to separate and deliver only particles within a predefined size range, minimizing clogging and ensuring consistent dosing.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Ease of operation
If pressurized fluid systems are used to deliver hemostatic agent, then the agent can be delivered to remote treatment sites, but the delivery rate and particulate size cannot be controlled, leading to clogging and inconsistent dosing
Solution Approach 1:
The delivery system is segmented into multiple lumens of different cross-sectional dimensions within the receiver. The first lumen receives particles from the handle, the second lumen with smaller cross-sectional dimension controls delivery to the delivery conduit, and the third lumen has intermediate dimensions. This segmentation allows different size particles to be directed through different pathways, enabling control over delivery rate and preventing clogging by filtering out oversized particles.
Solution Approach 2:
Different lumens are assigned different local qualities in terms of their cross-sectional dimensions. The first lumen has the largest cross-sectional dimension for receiving particles, the second lumen has a smaller dimension for controlled delivery, and the third lumen has an intermediate dimension. This local differentiation in geometric properties enables size-based particle separation and controlled dosing throughout the delivery process.
2Ease of operation
If pressurized fluid systems are used to deliver hemostatic agent, then the agent can be delivered to remote treatment sites, but the particulate size of the agent delivered cannot be controlled, resulting in inconsistent dosing
Solution Approach 1:
The receiver is divided into multiple lumens with specific cross-sectional dimensions that act as physical filters. The first lumen accepts particles of various sizes, while the second lumen with its smaller cross-sectional dimension only allows particles below a certain size threshold to pass through to the delivery conduit. This segmentation provides passive, reliable particulate size control without requiring complex active filtering mechanisms.
Solution Approach 2:
The system changes the geometric parameter of the lumens (cross-sectional dimension) to control particle flow. By designing lumens with specific dimension relationships (first lumen > third lumen > second lumen), the system passively sorts particles by size based on their ability to physically fit through each lumen, ensuring consistent dosing of appropriately sized particles.
Data Source
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Figure 4A~4B
AI summary
A medical device that includes a handle for conveying an agent having particles and a receiver having a first lumen defined by a first end and a second end. The receiver having an axis extending between the first end and the second end. The first end configured to receive the particles from the handle, and the second end in fluid communication with a second lumen having a cross-sectional dimension smaller than a cross-sectional dimension of the first lumen. Each of the cross- sectional dimensions of the first lumen and the second lumen is measured transverse to the axis. The second end is configured to receive the particles from the first end of the receiver. The second lumen is configured to control delivery of the agent to a delivery conduit in fluid communication with the second lumen based on sizes of the particles.