Pathological Cell Classification With Multi-Region Weighted Images

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Solution Overview

Problem

Existing techniques for pathological diagnosis struggle to accurately classify specimen cells as benign or malignant in pathological images, necessitating improved methods to enhance classification accuracy.

Innovation Solution

A classification apparatus and method utilizing multiple generative models to emphasize different regions of interest in pathological images, combined with feature analysis models to generate and classify feature quantities, and a training apparatus to update model parameters based on classification results.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If a single trained model is used for pathological image recognition, then the system is simple and fast, but the classification accuracy of specimen cells between benign and malignant is insufficient

Engineering Contradiction:
Improveclassification accuracyVSAvoidsystem complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent divides the single classification model into multiple specialized models, each responsible for analyzing specific regions of interest (e.g., nuclear region, cytoplasmic region). This segmentation allows each model to focus on particular features, thereby improving overall classification accuracy while maintaining manageable system complexity through modular architecture

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent introduces a new dimension of analysis by generating multiple weighted input images with different emphasis weights for different regions. Instead of analyzing the entire image uniformly, the system creates multiple versions of the image where different regions are emphasized, allowing the classification models to capture diverse features from different spatial dimensions

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

2Measurement precision

If multiple generative models are used to emphasize different regions, then the classification accuracy improves, but the processing time and computational resources increase

Engineering Contradiction:
Improveclassification accuracyVSAvoidprocessing time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The patent performs preliminary actions by pre-training multiple generative models and feature analysis models before actual classification tasks. The models are pre-trained on diverse pathological images with labeled regions, so that during actual classification, they can quickly generate weighted input images and extract features without requiring extensive real-time computation

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent creates multiple copies of the input pathological image through the generative models, where each copy is a weighted version emphasizing different regions. These copies are then processed by specialized feature analysis models. This copying approach allows parallel processing of multiple regional features simultaneously, improving accuracy while managing processing time through efficient model architecture

Inventive Principle:
Principle #26Copying

Data Source

PatentUS20250315953A1Classification apparatus, training apparatus, classification method, and storage medium
Publication Date: 2025.10.09 NEC CORP
  • US20250315953A1 patent drawing
  • US20250315953A1 patent drawing
  • US20250315953A1 patent drawing

AI summary

In order to improve accuracy in classification of a specimen cell between benignancy and malignancy in pathological diagnosis, a classification apparatus (1) includes: an acquisition section (11) for acquiring a pathological image; and a classification section (12) for classifying a specimen cell as a benign cell or a malignant cell using a classification model that receives input of (i) a feature quantity of a first weighted input image which has been processed with first weighting information for emphasizing a first region of interest and (ii) a feature quantity of a second weighted input image which has been processed with second weighting information for emphasizing a second region of interest which differs from the first region of interest.