Pathology Image Processing Using Adaptive Resolution Selection

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Solution Overview

Problem

Existing systems for processing pathology images are often slow, costly, and inefficient due to the large size and complexity of these images, which can limit their effective analysis and manipulation.

Innovation Solution

A method and system that utilize multiple representations of pathology image regions, with smaller data size alternatives, to determine when a lower-resolution representation can be used in place of a higher-resolution one based on specific image property criteria, leveraging machine learning models like convolutional neural networks for efficient processing and storage.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If higher-resolution representations are used for pathology image regions, then image quality and detail are improved, but processing speed and computational efficiency deteriorate

Engineering Contradiction:
Improveimage qualityVSAvoidprocessing speed
Core Design Contradiction:
Measurement precisionVSProductivity

Solution Approach 1:

The pathology image is divided into multiple regions of interest (ROIs), and each ROI is represented at different resolutions. The system segments the image into regions that require high resolution and regions that can use lower resolution, allowing parallel processing of multiple representations simultaneously.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The system dynamically selects between first and second representations based on processing needs and resource availability. The selection is not static but adapts based on the specific analysis task, allowing the system to optimize between quality and speed in real-time.

Inventive Principle:
Principle #15Dynamics

2Measurement precision

If higher-resolution representations are used for pathology image regions, then image detail is improved, but storage requirements and computational resources worsen

Engineering Contradiction:
Improveimage detailVSAvoidstorage requirements
Core Design Contradiction:
Measurement precisionVSQuantity of substance

Solution Approach 1:

The image data is segmented into multiple representations stored separately. Instead of storing one large high-resolution image, the system stores multiple smaller representations at different resolutions, reducing total storage requirements while maintaining access to high-detail regions when needed.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

Different regions of the pathology image are assigned different quality levels. Regions containing critical diagnostic features are maintained at high resolution, while other regions use lower resolution representations, optimizing the balance between detail preservation and storage efficiency.

Inventive Principle:
Principle #3Local quality

3Productivity

If multiple representations of image regions are maintained, then processing efficiency is improved, but system complexity worsens

Engineering Contradiction:
Improveprocessing efficiencyVSAvoidsystem complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The system pre-processes pathology images into multiple representations before actual analysis begins. This preliminary action creates a hierarchy of representations that can be quickly selected and combined during processing, avoiding the need to generate multiple resolutions on-demand and reducing real-time computational complexity.

Inventive Principle:
Principle #10Preliminary action

4Productivity

If lower-resolution representations are used, then processing cost and computational resources are reduced, but image quality deteriorates

Engineering Contradiction:
Improveprocessing costVSAvoidimage quality
Core Design Contradiction:
ProductivityVSMeasurement precision

Solution Approach 1:

The system segments the analysis task into regions requiring high resolution and regions where lower resolution suffices. By processing only critical regions at high resolution, the system maintains diagnostic quality where needed while reducing overall processing costs and computational resources.

Inventive Principle:
Principle #1Segmentation

Data Source

PatentUS11562485B1Processing pathology images
Publication Date: 2023.01.24 AIFORIA TECHNOLOGIES OY
  • US11562485B1 patent drawing
  • US11562485B1 patent drawing
  • US11562485B1 patent drawing

AI summary

A method of facilitating processing of pathology images involves receiving pathology image data representing a pathology image having a plurality of image regions, wherein the pathology image data includes, for each of the plurality of image regions, a respective plurality of representations of the image region including a first representation and a second representation, the second representation having a smaller data size than the first representation. The method involves, for each of the plurality of image regions: determining, based at least in part on the first representation of the image region, a first set of image properties, determining whether the first set of image properties meets first image property criteria, and, if the first set of image properties meets the first image property criteria, producing signals for causing the second representation to be used in place of the first representation. Other methods, systems, and computer-readable media are disclosed.