Patient Condition Prediction Model Using Synthetic Longitudinal Data

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Solution Overview

Problem

Existing patient condition prediction models face challenges in improving prediction accuracy due to insufficient learning data, as collecting actual patient conditions over time is difficult, limiting the generation of sufficient learning data needed for model updates.

Innovation Solution

A model generation apparatus and method that obtain learning data including index values indicating patient conditions at different times, using a prediction model to forecast future conditions based on past conditions and change information, allowing for model updates that incorporate predicted future condition values.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If actual patient condition data is collected to generate learning data, then prediction accuracy can be improved, but the amount of available learning data is insufficient

Engineering Contradiction:
Improveprediction accuracyVSAvoidamount of learning data
Core Design Contradiction:
Measurement precisionVSQuantity of substance

Solution Approach 1:

The system performs preliminary actions by generating synthetic learning data through simulation before actual patient data collection. The simulation generates predicted future condition values and change information that are used to create learning datasets, enabling model training to proceed even when actual longitudinal patient data is insufficient.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The system creates copies of patient condition data by simulating future conditions based on current state and change tendencies. Instead of requiring actual repeated measurements of the same patient over time, the system generates synthetic copies of what the condition values would be, effectively multiplying the available learning data without additional clinical measurements.

Inventive Principle:
Principle #26Copying

2Measurement precision

If more learning data is collected to improve prediction accuracy, then model performance improves, but the complexity of data collection and measurement increases

Engineering Contradiction:
Improveprediction accuracyVSAvoiddata collection complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The system performs self-service by using the prediction model itself to generate the learning data needed for its own training and improvement. The model generates predicted future condition values and change information that feed back into creating learning datasets, eliminating the need for external complex data collection systems to provide synthetic training data.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The system changes parameters by transforming current condition values and change tendencies into predicted future condition values through the prediction model. This parameter transformation generates synthetic learning data with different temporal characteristics without requiring physical changes to measurement systems or data collection procedures.

Inventive Principle:
Principle #35Parameter changes

3Measurement precision

If prediction accuracy is improved by using more actual patient data, then the model becomes more reliable, but the time required to collect sufficient data increases

Engineering Contradiction:
Improveprediction accuracyVSAvoiddata collection time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The system performs preliminary data generation actions by simulating patient condition trajectories in advance. Instead of waiting to collect actual patient data over extended periods, the system pre-generates learning datasets with predicted future conditions that can immediately be used for model training and validation.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The system adds a temporal dimension to data generation by creating synthetic future condition values based on change tendencies. This transforms static or limited cross-sectional patient data into pseudo-longitudinal learning datasets, effectively creating time-series learning data without requiring actual longitudinal observation periods.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

Data Source

PatentUS20240152778A1Model generation apparatus, model generation method, condition prediction apparatus, condition prediction method, and recording medium
Publication Date: 2024.05.09 NEC CORP
  • US20240152778A1 patent drawing
  • US20240152778A1 patent drawing
  • US20240152778A1 patent drawing

AI summary

A model generation apparatus includes: an acquisition unit for obtaining learning data including a first index value indicating a condition of a sample patient at a first time, and a second index value indicating a condition of the sample patient at a second time that is after the first time; and a learning unit for learning a prediction mode for predicting a condition of a target patient at the second time on the basis of a condition of the target patient at the first time, wherein the learning unit is configured to learn the prediction model by updating the prediction model on the basis of a third index value indicating a condition of the sample patient at the second time that is predicted by the prediction model on the basis of the first index value, and a change information indicating a change tendency of the condition over time.