Patient-Specific Immunotherapy Scheduling With Identity Tracking

Resolve Bottlenecks,
Find Innovative SolutionsGenerate Solutions

Solution Overview

Problem

Existing immunotherapy procedures lack dynamic scheduling flexibility, real-time updates, and effective chain-of-custody and chain-of-identity tracking for patient-specific biological samples, leading to potential delays and misidentification issues.

Innovation Solution

A dynamic scheduling system with real-time updates and chain-of-custody tracking, utilizing a scheduling module that integrates with a server computing device and database to manage leukapheresis appointments, apheresis kit delivery, and cell infusion, ensuring patient-specific tracking and scheduling flexibility.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If existing immunotherapy procedures are used, then the treatment can be provided to patients, but the procedures lack dynamic scheduling flexibility and real-time updates, leading to delays in manufacturing and treatment

Engineering Contradiction:

Improvespeed of providing modified biological material to patientVSAvoiddelays in manufacturing process

Core Design Contradiction:

ProductivityVSLoss of time

Solution Approach 1:

The patent implements a dynamic scheduling calendar that allows real-time modification of treatment dates and times. The system automatically updates all related appointments (leukapheresis, manufacturing, infusion) when changes are made, enabling flexible adaptation to patient needs and manufacturing capacity without manual re-scheduling, thus reducing delays while maintaining treatment effectiveness.

Inventive Principle:

Principle #15Dynamics

Solution Approach 2:

The system provides real-time notifications and updates to all stakeholders (patients, physicians, manufacturing staff) about scheduling changes and treatment status. This feedback mechanism ensures everyone is immediately aware of changes, preventing delays caused by communication gaps and enabling rapid response to any issues in the manufacturing or treatment process.

Inventive Principle:

Principle #23Feedback

2Reliability

If existing immunotherapy procedures are used, then treatment can be provided, but there is no automatic tracking mechanism for patient's biological material, resulting in potential mislabeling and misidentification

Engineering Contradiction:

Improveaccuracy of biological material trackingVSAvoidchain of custody and chain of identity information

Core Design Contradiction:

ReliabilityVSLoss of information

Solution Approach 1:

The system creates and maintains digital copies of all biological material identifiers (barcodes, patient IDs, sample IDs) throughout the chain of custody. Each transfer, storage, and processing event is recorded with these identifier copies, ensuring that the biological material can be accurately traced and identified at any point in the process, preventing mislabeling and misidentification.

Inventive Principle:

Principle #26Copying

Solution Approach 2:

The patent introduces a central computing system as an intermediary that manages and tracks all biological material information. This system serves as a mediator between patients, physicians, and manufacturing facilities, maintaining the chain of custody and chain of identity records, and ensuring accurate tracking without requiring direct communication between all parties.

Inventive Principle:

Principle #24Intermediary (Mediator)

3Ease of operation

If existing immunotherapy procedures are used, then treatment can be provided, but there are no real-time updates to multiple users involved in the process, leading to lack of coordination and potential delays

Engineering Contradiction:

Improvecoordination among multiple usersVSAvoidtime for manual coordination and updates

Core Design Contradiction:

Ease of operationVSLoss of time

Solution Approach 1:

The scheduling system serves multiple functions simultaneously: it manages appointments, tracks biological material, sends notifications, updates treatment status, and coordinates between patients, physicians, and manufacturing staff. This multi-functional system eliminates the need for separate communication channels and manual coordination, reducing time loss while improving ease of operation for all users.

Inventive Principle:

Principle #6Universality (Multi-functionality)

Data Source

PatentUS20250279189A1Methods and systems for scheduling a patient-specific immunotherapy procedure

Publication Date: 2025.09.04 KITE PHARMA INC

AI summary

A method and system for scheduling a patient-specific immunotherapy procedure. The method includes receiving a request on a server computing device to schedule a leukapheresis appointment for an available date and time displayed on a calendar stored in a database that is in communication with the computing device. The request can be made with a client computing device that is in communication with the server computing device via a network. Furthermore, the calendar may be updated in real time by the server computing device to show any changes to the calendar. The server computing device may automatically generate a final product date to estimate when the final product of engineered cells from the patient will be available for infusion into the patient. A manufacturing processing status for the final product of engineered cells from the patient may be updated on the calendar.