PCCT Calibration Using a Non-Uniform Phantom for Low-Contrast Detection

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Solution Overview

Problem

Conventional CT imaging systems, particularly photon counting CT (PCCT) systems, face challenges in accurately calibrating to detect small and low-contrast features due to non-ideal detector responses such as charge sharing and detector crosstalk, which degrade resolution and contrast-to-noise ratio.

Innovation Solution

A non-uniform phantom is used to calibrate a photon counting CT scanner, which includes a non-uniform phantom, which includes a plurality of slots of various sizes, shapes, and depths filled with different materials to simulate clinical features, allowing for a correction factor to be calculated and applied to adjust the calibration algorithm, thereby calibrating the detector, and a calibration process, which includes a calibration algorithm based on the correction factor.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If conventional CT imaging systems use standard calibration methods, then the calibration process is simple and quick, but the accuracy of detecting small and low-contrast features is degraded due to non-ideal detector responses such as charge sharing and detector crosstalk

Engineering Contradiction:
Improveaccuracy of detecting small and low-contrast featuresVSAvoidcomplexity of calibration process
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The phantom incorporates multiple slots with different sizes, shapes, and depths filled with different materials to simulate various clinical features. Each slot represents a specific local quality or contrast level, allowing the calibration process to address different detection challenges simultaneously. This local differentiation enables the system to calibrate for specific detector response artifacts like charge sharing and crosstalk in a targeted manner.

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

The non-uniform phantom serves as an intermediary object between the X-ray source/detector system and the calibration algorithm. By placing known composition features (slots with specific materials) in controlled positions, the phantom mediates the calibration process, allowing the system to measure and correct detector responses without requiring direct manipulation of the detector hardware or complex mathematical modeling alone.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Measurement precision

If a non-uniform phantom with multiple slots of various sizes and shapes is used, then the calibration accuracy for small and low-contrast features is improved, but the phantom complexity and manufacturing difficulty increase

Engineering Contradiction:
Improvecontrast-to-noise ratio and resolutionVSAvoidphantom manufacturing complexity
Core Design Contradiction:
Measurement precisionVSEase of manufacture

Solution Approach 1:

The phantom is segmented into multiple discrete slots of different sizes, shapes, and depths, each filled with specific materials. This segmentation allows for modular construction and easier manufacturing compared to creating a completely non-uniform structure from scratch. Each slot can be independently fabricated and assembled, reducing overall manufacturing complexity while maintaining the necessary variability for accurate calibration.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The phantom utilizes composite materials by filling different slots with various materials that have known and distinct composition properties. This approach allows the phantom to simulate different tissue densities and contrast characteristics. The use of standardized composite materials and pre-fabricated components simplifies the manufacturing process while achieving the desired non-uniform structure for calibration purposes.

Inventive Principle:
Principle #40Composite materials

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The non-uniform phantom enhances the visibility of small and low-contrast features by adjusting the calibration algorithm, improving the accuracy and quality of PCCT system images.

Implementation Method 1

A fan-shaped or cone-shaped beam of X-rays produced by electrons colliding with the target is directed towards a subject, such as a patient. After being attenuated by the object, the X-rays impinge upon an array of X-ray detectors

Methodology Applied
Scientific EffectX-ray attenuation: Absorption (EM radiation)

Implementation Method 2

the X-rays impinge upon an array of X-ray detectors, generating an image. One example of a CT system is a photon counting CT (PCCT), where the X-ray detectors are photon-counting detectors, and photons are counted to provide spectral information

Methodology Applied
Scientific EffectPhotoelectric effect: Photoelectric Effect

Data Source

PatentUS20250366813A1Systems and methods for computed tomography calibration
Publication Date: 2025.12.04 GE PRECISION HEALTHCARE LLC
  • US20250366813A1 patent drawing
  • US20250366813A1 patent drawing
  • US20250366813A1 patent drawing

AI summary

Embodiments of a method for calibrating an imaging system are disclosed herein. In one example, the method includes generating a detector response prediction for one or more composition features of a non-uniform phantom, scanning the non-uniform phantom at a plurality of positions between an X-ray source and a detector of the imaging system, measuring an actual detector response at each position, generating a correction factor based on the detector response prediction and adjusting one or more calibration algorithms based on the correction factor.