PCED Detector Housing for Integrated Tissue Imaging
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Solution Overview
Problem
Existing medical imaging systems struggle to provide both diagnostic and histopathologic images of biopsy samples on a single platform, leading to delays in obtaining timely histopathology results.
Innovation Solution
A tissue imaging system integrated with a radiography imaging system, featuring a photon counting energy discriminating (PCED) detector within a housing on the detector surface, capable of generating multi-energy material decomposition images, material enhanced images, 2D/3D image tomographic reconstruction images, and phase contrast images.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If biopsy samples are sent to a separate histopathology imaging system for detailed tissue classification, then high-resolution histopathology images can be obtained, but time is lost due to sample transport and separate imaging procedures
Solution Approach 1:
The patent combines the mammography imaging system and histopathology imaging system into a single integrated platform. The histopathology imaging device is positioned adjacent to the mammography detector, allowing biopsy samples to be imaged immediately after removal from the patient without transport to a separate facility. This merging eliminates the time loss associated with sample transport and separate imaging procedures while maintaining high-resolution histopathology imaging capabilities.
2Loss of time
If a single imaging system is used for both diagnostic and histopathology imaging, then time is saved by eliminating sample transport, but the system complexity increases
Solution Approach 1:
The integrated imaging system is designed to perform multiple functions: diagnostic mammography imaging and high-resolution histopathology imaging of biopsy samples. The system includes a mammography imaging device and a histopathology imaging device that can be selectively activated based on the imaging needs. This multi-functionality allows the system to eliminate sample transport time while managing complexity through a modular design where each imaging modality can operate independently when needed.
3Reliability
If separate imaging systems are used for diagnostic and histopathology purposes, then each system can be optimized for its specific function, but the overall process efficiency decreases due to sample handling and transport
Solution Approach 1:
The integrated system is segmented into distinct functional modules: a mammography imaging device for diagnostic imaging and a histopathology imaging device for detailed tissue analysis. Each module can be independently optimized for its specific imaging function while being physically integrated to allow immediate sample imaging. This segmentation maintains the functional optimization benefits of separate systems while eliminating the inefficiencies of sample transport and handling between facilities.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Enables the generation of high-resolution images of biopsy samples, allowing for precise classification of tissue types and reducing the need for separate histopathology imaging systems, thereby improving the timeliness of diagnostic results.
Implementation Method 1
a photon counting energy discriminating (PCED) detector disposed within the interior of the housing
Implementation Method 2
a photon counting energy discriminating (PCED) detector disposed within the interior of the housing
Implementation Method 3
phase contrast images of the imaged tissue
Implementation Method 4
2D/3D image tomographic reconstruction images
Data Source
AI summary
A tissue imaging system for use in conjunction with a radiography imaging system including a radiation source and a detector includes a tissue imaging device adapted to be positioned on a surface of the detector of the radiography imaging system between the radiation source and the detector. The tissue imaging device includes a housing positionable on the surface of the detector, the housing defining an interior and a tissue support surface opposite the surface of the detector and a photon counting energy discriminating (PCED) detector disposed within the interior of the housing. The PCED detector is removably connected to the radiography imaging system and is operable to generate image data used to form one or more of multi-energy material decomposition images, material enhanced images, 2D/3D image tomographic reconstruction images, and phase contrast images of the imaged tissue positioned on the tissue support surface.