Antibacterial Cleansing Composition Using PCMX and IPMP
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Solution Overview
Problem
There is a need for alternative antibacterial agents as effective as triclosan and triclocarban for personal hygiene products, particularly cleansing liquids and bars, to provide long-lasting antibacterial effects without the use of these common agents.
Innovation Solution
A personal care composition comprising chloroxylenol (PCMX), o-cymen-5-ol (IPMP), and phenoxyethanol, with PCMX present in 0.2-0.6% and IPMP in 0.05-0.5% by weight, providing effective antibacterial properties against both gram-positive and gram-negative bacteria, and optionally including phenoxyethanol in 0.1-2% by weight, without triclosan or triclocarban.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If triclosan and triclocarban are used as antibacterial agents, then high antibacterial efficacy is achieved, but the need for alternative agents arises due to their widespread use and potential concerns
Solution Approach 1:
The patent changes the chemical parameters by substituting triclosan and triclocarban with a different chemical system comprising chloroxylenol, o-cymen-5-ol, and phenoxyethanol. This parameter change maintains antibacterial efficacy while providing an alternative to widely used agents, resolving the contradiction between reliability and adaptability.
Solution Approach 2:
The patent employs a composite antibacterial system combining three different compounds (chloroxylenol, o-cymen-5-ol, and phenoxyethanol) to achieve the antibacterial effect. This composite approach provides versatility and alternatives to single-agent systems like triclosan or triclocarban, while maintaining high efficacy through synergistic interactions.
2Reliability
If conventional antibacterial soaps are used, then bacterial elimination is effective, but long-lasting antibacterial effects are needed to improve duration of action
Solution Approach 1:
The patent achieves continuous antibacterial protection by formulating a composition that maintains active antibacterial agents on the skin surface over extended periods. The combination of chloroxylenol, o-cymen-5-ol, and phenoxyethanol provides sustained release and continuous action, transforming the intermittent cleansing action into prolonged protective effect.
Solution Approach 2:
The composition is designed to establish antibacterial protection in advance and maintain it over time. By incorporating long-lasting antibacterial agents that persist on the skin, the system provides preliminary and sustained action beyond the immediate cleansing moment, addressing the need for extended duration of effect.
3Adaptability or versatility
If alternative antibacterial agents are sought, then adaptability is improved, but achieving comparable efficacy to triclosan and triclocarban becomes challenging
Solution Approach 1:
The patent merges three different antibacterial compounds (chloroxylenol, o-cymen-5-ol, and phenoxyethanol) into a single composition to achieve synergistic effects. This combination approach allows the alternative system to match or exceed the efficacy of triclosan and triclocarban by leveraging the complementary actions of multiple agents rather than relying on a single compound.
Solution Approach 2:
The use of a composite system of three antibacterial agents provides both adaptability as an alternative to conventional single-agent soaps and reliability through the combined efficacy of the components. The composite nature allows the formulation to achieve high antibacterial performance while remaining distinct from triclosan and triclocarban-based products.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The composition demonstrates high antibacterial efficacy, comparable to triclocarban-based compositions, effectively reducing bacterial populations on skin surfaces, providing long-lasting antibacterial effects and compatibility in soap mixes with a pH above 8.0.
Implementation Method 1
the antibacterial component comprising chloroxylenol (PCMX), o-cymen-5-ol (IPMP); and phenoxyethanol, wherein the PCMX is present in an amount of about 0.2% to about 0.6% by weight of the composition, wherein the IPMP is present in an amount of about 0.05% to about 0.5% by weight of the composition, wherein the phenoxyethanol is present in an amount of about 0.1% to about 2% by weight of the composition
Data Source
AI summary
Described herein, are personal care compositions comprising an effective amount of an antibacterial component selected from chloroxylenol (PCMX) and o-cymene-5-on (IPMP); phenoxyethanol; piroctone olamine; and a surfactant. Methods of making and using these compositions are also described.