PCT11204V Cannabis Variety Elevating THCV Levels

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Solution Overview

Problem

Cannabis plants naturally have low levels of varin cannabinoids, such as THCV and CBDV, limiting research and product development due to their rarity, which hampers the creation of high-margin medical and recreational products with distinct pharmacological profiles.

Innovation Solution

A novel Cannabis sativa variety, 'PCT11204V', is developed through selective breeding and marker-assisted selection to elevate THCV levels, achieved by crossing high THCV pollen receiver and THC pollen donor plants, ensuring consistent and high production of varins through asexual propagation.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Quantity of substance

If conventional Cannabis plants are used, then cultivation is simple and well-established, but varin levels (THCV, CBDV) are naturally low limiting product development

Engineering Contradiction:
Improvevarin levelsVSAvoidbreeding program complexity
Core Design Contradiction:
Quantity of substanceVSDevice complexity

Solution Approach 1:

The patent applies preliminary action by pre-establishing a structured breeding program with defined parental lines (high THCV receiver × high THC donor) and marker-assisted selection protocols before large-scale production. This preliminary setup enables systematic elevation of varin levels across generations without ad-hoc complexity during production

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent implements feedback through marker-assisted selection where molecular markers are used to track and select for elevated THCV and CBDV levels in progeny. This feedback mechanism ensures that breeding efforts consistently achieve the desired varin concentration targets, resolving the contradiction between increased varin levels and breeding complexity

Inventive Principle:
Principle #23Feedback

2Quantity of substance

If selective breeding and marker-assisted selection are used to elevate THCV levels, then varin production increases, but breeding and selection time increases

Engineering Contradiction:
ImproveTHCV contentVSAvoidbreeding and selection time
Core Design Contradiction:
Quantity of substanceVSLoss of time

Solution Approach 1:

The patent replaces traditional mechanical/phenotypic selection methods with marker-assisted selection using molecular markers. This substitution accelerates the breeding process by enabling early-generation selection based on genetic markers rather than waiting for phenotypic expression, significantly reducing the time required to develop high-THCV varieties while maintaining selection precision

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent changes the selection parameter from phenotypic observation to molecular marker detection. By using DNA markers linked to THCV synthesis genes, the breeding program can select for elevated THCV content at the molecular level, accelerating the breeding timeline while achieving the desired parameter changes in varin production

Inventive Principle:
Principle #35Parameter changes

3Stability of the object's composition

If asexual propagation is used to fix genetic loci, then genetic stability is improved, but propagation infrastructure requirements increase

Engineering Contradiction:
Improvegenetic loci stabilityVSAvoidpropagation infrastructure
Core Design Contradiction:
Stability of the object's compositionVSDevice complexity

Solution Approach 1:

The patent applies self-service by using asexual propagation through vegetative cuttings that naturally maintain genetic fidelity without requiring complex intervention. The cloned plants inherently preserve the fixed genetic loci for THCV synthesis, achieving genetic stability through the biological self-service of clonal reproduction rather than requiring elaborate external control systems

Inventive Principle:
Principle #25Self-service

Data Source

PatentUSPP35172P2<i>Cannabis </i>plant named ‘PCT11204V’
Publication Date: 2023.05.16 PHYLOS BIOSCIENCE INC
  • USPP35172P2 patent drawing

AI summary

A new and distinct variety of Cannabis sativa designated ‘PCT11204V’ as herein described and illustrated, characterized by elevated levels of THCV and other varin cannabinoids.