Peanut Skin Extract Increases PTPRD Gene Expression
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Solution Overview
Problem
Current methods do not effectively utilize peanut skins, considered waste, for preventing or treating cancers related to the PTPRD gene, which is a tumor suppressor gene with low expression in liver and gastric cancers.
Innovation Solution
A peanut skin extract is obtained using a polar solvent, preferably water, and formulated into a pharmaceutical or food composition to increase PTPRD gene expression, which can be administered orally, intravenously, or subcutaneously for cancer prevention and treatment.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Loss of substance
If peanut skin is discarded as waste, then resource waste is minimized, but potential therapeutic value for cancer treatment is lost
Solution Approach 1:
The patent converts the previously discarded peanut skin waste into a valuable therapeutic resource by extracting active components that can treat liver and gastric cancers. The extraction process transforms the harmful waste material into a beneficial pharmaceutical composition that restores PTPRD gene expression and kills cancer cells.
Solution Approach 2:
The patent applies extraction technology to isolate active components from peanut skin. Through solvent extraction and purification processes, the patent recovers bioactive substances from the waste material, creating a concentrated pharmaceutical composition that can be administered for cancer treatment.
2Productivity
If conventional extraction methods are used, then extraction speed is maintained, but extraction efficiency and component recovery are insufficient
Solution Approach 1:
The patent optimizes extraction parameters including solvent type, temperature, pH level, and extraction time to maximize the recovery of active components from peanut skin. By carefully controlling these parameters, the patent achieves both high extraction efficiency and maintained productivity.
Solution Approach 2:
The patent employs composite extraction systems combining multiple solvents and processing steps to efficiently recover diverse active components from peanut skin. This composite approach allows simultaneous extraction of multiple bioactive substances that would be difficult to isolate using single-method approaches.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The peanut skin extract significantly increases PTPRD gene expression, providing effective prevention and treatment options for liver and gastric cancers, as demonstrated by increased expression levels in cell cultures.
Implementation Method 1
the peanut skin extract is effective in increasing the expression of PTPRD gene
Implementation Method 2
the extract is obtained by extracting the peanut skin with a polar solvent
Data Source
AI summary
A method for increasing the expression of PTPRD gene is provided, wherein the method comprises administering to a subject in need an effective amount of a peanut skin extract. The method is effective in preventing or treating diseases related to PTPRD gene.