Pentadecanoic Triglyceride Composition for Collagen and Wrinkle Repair
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Solution Overview
Problem
Wrinkles are caused by a decrease in type I collagen production in the skin, and existing cosmetic solutions have not effectively addressed this issue due to the lack of effective substances that promote collagen production.
Innovation Solution
The use of naturally occurring triglyceride compounds, particularly those containing pentadecanoic acid residues, to promote collagen production and improve wrinkles through topical skin care compositions and beauty foods/beverages.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If conventional cosmetic substances are used to promote collagen production, then skin aging prevention is attempted, but the effectiveness is insufficient due to lack of potent active ingredients
Solution Approach 1:
The patent changes the chemical parameter of the active ingredient from conventional cosmetic substances to triglycerides containing odd-chain fatty acids (specifically C15:0, C17:0, C19:0). This parameter change results in significantly enhanced collagen production promotion effectiveness while maintaining skin compatibility.
Solution Approach 2:
The patent introduces triglycerides containing odd-chain fatty acids as an intermediary substance that mediates between the skin and collagen production. These triglycerides serve as effective carriers and active ingredients that directly stimulate fibroblast activity and collagen synthesis, overcoming the limitations of conventional cosmetic substances.
2Productivity
If triglycerides containing odd-chain fatty acids are used as active ingredients, then collagen production is significantly promoted, but the difficulty of obtaining these substances increases
Solution Approach 1:
The patent utilizes Aurantiochytrium algae as a self-service production system that naturally synthesizes and accumulates triglycerides containing odd-chain fatty acids. The algae culture system serves itself to produce the required active ingredients, eliminating the need for complex extraction or synthesis processes and making the substances easily obtainable.
Solution Approach 2:
The patent employs Aurantiochytrium algae as a multi-functional system that simultaneously serves as a production platform for triglycerides containing odd-chain fatty acids and as a source of other beneficial compounds. This universal approach simplifies manufacturing by obtaining multiple active ingredients from a single biological source.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The triglyceride compounds significantly enhance collagen production in human fibroblasts, effectively preventing and improving skin aging by maintaining the TCA cycle and promoting type I collagen synthesis, thus reducing wrinkles.
Implementation Method 1
Odd-chain fatty acids, like even-chain fatty acids, can be used as an energy source through β-oxidation, but they also function to maintain the TCA cycle normally by converting propionyl-CoA, the last product of odd-chain fatty acids in the β-oxidation system, to succinyl-CoA
Implementation Method 2
the triglyceride compound acts on human fibroblasts to cause them to produce type I collagen significantly
Data Source
AI summary
Provided is a collagen production promoter comprising, as an active ingredient, a triglyceride represented by the following formula (I), wherein R1, R2 and R3 each denotes a saturated fatty acid residue, at least one of which is a pentadecanoic acid residue. The triglyceride comprising the pentadecanoic acid promotes the production of skin fibroblasts and collagen, and can be used as a topical skin care composition and a beauty food or beverage for improving the condition of skin.