Pentosan Polysulfate Topical Moisturizer
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Solution Overview
Problem
Conventional topical moisturizers often rely on animal-derived components, raising ethical concerns and lacking effective alternatives for plant-derived moisturizing agents.
Innovation Solution
A topical moisturizing preparation utilizing pentosan polysulfate, a plant-derived substance, which exhibits excellent moisturizing efficacy and can be formulated as an aqueous solution with specific uronic acid and acetyl group content, providing a non-animal-derived component solution.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If animal-derived polysulfated mucopolysaccharides (heparin) are used as moisturizers, then effective moisturizing action is achieved, but ethical concerns arise and quality control becomes difficult
Solution Approach 1:
The patent replaces expensive, ethically problematic animal-derived heparin with a plant-derived pentosan polysulfate alternative that is more readily available and easier to produce consistently, effectively substituting a scarce resource with an abundant one
Solution Approach 2:
The patent changes the source material parameter from animal-derived to plant-derived polysulfated mucopolysaccharides, specifically using pentosan polysulfate with controlled uronic acid content (0-15%) and acetyl group content (0-2%), thereby maintaining moisturizing efficacy while eliminating ethical and quality control issues
2Object-affected harmful factors
If plant-derived pentosan polysulfate is used as a moisturizer, then ethical concerns are eliminated and quality control is easier, but the moisturizing action was previously unknown
Solution Approach 1:
The patent demonstrates that pentosan polysulfate, a plant-derived substance already known for other therapeutic uses, inherently possesses moisturizing properties that can be directly applied to skin care applications without requiring complex modification or additional components
Solution Approach 2:
The patent establishes specific parameter ranges for pentosan polysulfate (uronic acid content: 0-15%, acetyl group content: 0-2%, dispersion degree: 1.00-1.40) to optimize and guarantee moisturizing efficacy, transforming an unknown substance into a reliably effective moisturizer
3Reliability
If conventional moisturizers are used, then moisturizing effect is achieved, but animal-derived components raise ethical hesitation
Solution Approach 1:
The patent substitutes animal-derived materials with plant-derived pentosan polysulfate, which is more abundant and ethically acceptable, while maintaining the functional performance required for moisturizing
Solution Approach 2:
The patent changes the biological source parameter from animal to plant origin while controlling chemical composition parameters (uronic acid content, acetyl group content) to ensure the alternative material achieves comparable or superior moisturizing effects
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The pentosan polysulfate-based preparation effectively maintains and increases skin water content, offering additional benefits like anti-inflammatory and anti-aging effects while being free from animal-derived components, ensuring easier quality control.
Implementation Method 1
the inventors have found that pentosan polysulfate can exhibit excellent efficacy as a topical moisturizing preparation
Data Source
AI summary
The present invention provides a novel topical moisturizing preparation containing as an active ingredient at least one selected from pentosan polysulfate; pharmaceutically acceptable salts of pentosan polysulfate; and pharmaceutically acceptable solvates thereof. The topical moisturizing preparation of the present invention, which contains a substance free of animal-derived components as an active ingredient, can be produced as a topical moisturizing preparation free of animal-derived components, as needed.