Peptide Hair Composition for Cortex Penetration and Strengthening

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Solution Overview

Problem

Current hair treatment methods using harmful chemicals like sodium hydroxide, potassium hydroxide, and formaldehyde damage the hair fiber and scalp, while less damaging treatments are expensive or ineffective, and peptides struggle to penetrate and effectively interact with the hair cortex to improve mechanical properties.

Innovation Solution

A peptide composition with 11-12 amino acids, including 2-3 cysteines, is designed to penetrate the hair cortex, forming disulfide bonds and enhancing hair strength and hydrophobicity, using excipients suitable for dermatology.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If harmful chemicals like sodium hydroxide, potassium hydroxide, and formaldehyde are used for hair treatment, then hair modeling effectiveness is improved, but hair fiber damage and scalp damage increase

Engineering Contradiction:
Improvehair modeling effectivenessVSAvoidhair fiber damage and scalp damage
Core Design Contradiction:
ProductivityVSObject-affected harmful factors

Solution Approach 1:

The invention changes the chemical parameters by using peptides with specific amino acid sequences (11-12 amino acids, 2-3 cysteines) instead of traditional harsh chemicals. This parameter change allows effective hair treatment through disulfide bond formation without the damaging effects of strong alkalis and formaldehyde

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The peptide composition acts as an intermediary substance that facilitates hair treatment by forming disulfide bonds with hair proteins. This intermediary approach replaces direct damage from harsh chemicals with a gentler molecular mediation process that achieves similar structural modification without the harmful side effects

Inventive Principle:
Principle #24Intermediary (Mediator)

2Object-affected harmful factors

If less damaging treatments are used to avoid harm to hair and scalp, then hair fiber damage is reduced, but treatment effectiveness decreases and cost increases

Engineering Contradiction:
Improvehair fiber damageVSAvoidtreatment effectiveness
Core Design Contradiction:
Object-affected harmful factorsVSProductivity

Solution Approach 1:

The invention optimizes the molecular parameters of the treatment agent by designing peptides with specific characteristics (11-12 amino acid length, 2-3 cysteine residues) that enable effective hair cortex penetration and disulfide bond formation, achieving high treatment effectiveness without the damage associated with traditional methods

Inventive Principle:
Principle #35Parameter changes

3Strength

If peptides are used to treat hair, then hair strength is improved, but peptide penetration into hair cortex is difficult

Engineering Contradiction:
Improvehair strengthVSAvoidpeptide penetration into hair cortex
Core Design Contradiction:
StrengthVSEase of operation

Solution Approach 1:

The invention optimizes the physical parameters of the peptide molecules by controlling their size (11-12 amino acids) and chemical composition (2-3 cysteines), which enables effective penetration into the hair cortex while maintaining the ability to form strengthening disulfide bonds

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The peptide composition is designed with pre-optimized molecular characteristics that facilitate cortex penetration before the actual treatment action occurs. The specific amino acid sequence and molecular size are predetermined to enable easy penetration, allowing the strengthening effect to occur without penetration resistance

Inventive Principle:
Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The peptide composition strengthens and protects hair from water damage, providing smooth, glossy, and undamaged hair with improved elasticity and toughness without using harmful chemicals.

Implementation Method 1

The presence of sulfur is essential for hair structure, since it allows the formation of disulfide bonds between polypeptide chain of amino acids, due to oxidation of cysteine residues

Methodology Applied
Scientific EffectDisulfide bond formation: Chemical Bonding

Implementation Method 2

The presence of sulfur is essential for hair structure, since it allows the formation of disulfide bonds between polypeptide chain of amino acids, due to oxidation of cysteine residues

Methodology Applied
Scientific EffectOxidation: Oxidation

Implementation Method 3

enhancing hair strength and hydrophobicity

Methodology Applied
Scientific EffectHydrophobic interaction: Hydrophobe

Data Source

PatentUS12357556B2Composition for improving hair health
Publication Date: 2025.07.15 K18 INC
  • US12357556B2 patent drawing
  • US12357556B2 patent drawing
  • US12357556B2 patent drawing

AI summary

A composition comprising two peptides with a size of 11 and 12 amino acids, wherein 2-3 of said amino acids are cysteines and a suitable dermatology excipient, which can be used for treatment and grooming products for animal hair, preferably for treatment and cosmetics for human hair.