Peptide-Based Nutritional Composition for Adiponectin Stimulation
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Solution Overview
Problem
Obesity, particularly in children, is increasing and associated with various health issues, and existing solutions do not effectively promote adiponectin production, which is crucial for metabolic health and weight management.
Innovation Solution
A nutritional composition containing specific peptides, such as those listed in SEQ ID NO 4, 13, 17, 21, 24, 30, 31, 32, 51, 57, and 60, is provided to stimulate adiponectin production and promote healthy body weight by including these peptides as a protein equivalent source, which can comprise 20-80% of the composition, along with intact or hydrolyzed proteins.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If conventional nutritional compositions are used, then basic nutritional needs are met, but adiponectin production is not effectively stimulated
Solution Approach 1:
The patent applies parameter changes by modifying the nutritional composition to include specific peptides (SEQ ID NO: 4, 13, 17, 21, 24, 30, 31, 32, 51, 57, 60) at optimized concentrations. These peptide parameters are selected and formulated to specifically stimulate adiponectin production, transforming a conventional nutritional composition into one with enhanced metabolic health benefits and reliable adiponectin stimulation capability.
2Reliability
If obesity treatment methods are applied, then body weight may be reduced, but metabolic health and adiponectin levels are not improved
Solution Approach 1:
The patent uses specific peptides as intermediary substances that mediate between nutritional intake and adiponectin production. These peptides act as signaling molecules that trigger adiponectin synthesis in adipocytes, thereby improving metabolic health and reducing body fat accumulation through a controlled biological pathway rather than direct weight loss methods.
3Reliability
If early life nutritional intervention is implemented, then adiponectin levels can be improved, but requires specialized peptide formulations
Solution Approach 1:
The patent employs composite material principles by formulating a complex peptide mixture containing multiple specific peptides (SEQ ID NO: 4, 13, 17, 21, 24, 30, 31, 32, 51, 57, 60) in defined proportions. This composite peptide formulation works synergistically to stimulate adiponectin production in early life, achieving reliable metabolic health benefits while managing the complexity through standardized formulation.
Data Source
AI summary
The present disclosure relates to nutritional compositions including a protein equivalent source that includes a peptide component comprising selected peptides. The protein equivalent source may further include intact protein, hydrolyzed protein, including partially hydrolyzed protein, or combinations thereof. The disclosure further relates to methods of promoting healthy body weight in a target subject by stimulating adiponectin levels by providing the nutritional compositions disclosed herein to a target subject, which includes a pediatric subject.