Peptide Botanical Topical Composition for Skin Firmness and Cellulite

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Solution Overview

Problem

There is a need for an easy-to-use topical composition that can improve skin laxity, tighten, tone, smooth, and/or firm skin and/or reduce cellulite, addressing issues such as skin thinning, loss of elasticity, and sagging due to aging or environmental factors.

Innovation Solution

A topical composition comprising tripeptides, tetrapeptides, botanical extracts as ECM, CR, and AT agents, along with antioxidants, applied to various skin areas to enhance collagen and elastin production, improve skin firmness, and reduce cellulite.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Strength

If topical composition is applied to improve skin laxity and firmness, then skin firmness and elasticity are improved, but the composition complexity increases due to multiple peptide and botanical extract components

Engineering Contradiction:
Improveskin firmnessVSAvoidcomposition complexity
Core Design Contradiction:
StrengthVSDevice complexity

Solution Approach 1:

The composition is segmented into distinct functional modules: tripeptides for collagen stimulation, tetrapeptides for elastin production, botanical extracts for antioxidant support, and adipose-targeting agents for cellulite reduction. Each module addresses specific aspects of skin aging independently, allowing the complex formulation to be managed as organized functional units rather than a random mixture of ingredients.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The invention employs a composite formulation strategy by combining multiple types of peptides (tripeptides and tetrapeptides) with various botanical extracts and adipose-targeting agents. This composite approach creates a synergistic effect where each component contributes unique properties, achieving comprehensive skin firmness improvement that single-ingredient formulations cannot accomplish.

Inventive Principle:
Principle #40Composite materials

2Reliability

If multiple active ingredients are included to address skin thinning and loss of elasticity, then the effectiveness of skin treatment is improved, but the manufacturing precision requirements increase

Engineering Contradiction:
Improvetreatment effectivenessVSAvoidformulation precision
Core Design Contradiction:
ReliabilityVSManufacturing precision

Solution Approach 1:

The formulation specifies precise concentration ranges for each active ingredient (tripeptides at 0.001-1%, tetrapeptides at 0.001-1%, botanical extracts at 0.1-10%) to optimize treatment effectiveness while managing manufacturing complexity. These parameter specifications provide clear manufacturing targets that balance therapeutic efficacy with production feasibility.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

Different regions of the formulation serve specialized functions: tripeptides are positioned for deep dermal penetration to stimulate collagen, tetrapeptides target elastin fiber production in the mid-dermis, while botanical extracts provide surface-level antioxidant protection. This spatial-functional differentiation ensures each ingredient works optimally in its designated zone, improving overall treatment reliability.

Inventive Principle:
Principle #3Local quality

3Stability of the object's composition

If the composition targets both collagen and elastin production, then skin elasticity is improved, but the quantity of substance required increases

Engineering Contradiction:
Improveskin elasticityVSAvoidamount of active ingredients
Core Design Contradiction:
Stability of the object's compositionVSQuantity of substance

Solution Approach 1:

The invention merges collagen-stimulating tripeptides and elastin-producing tetrapeptides into a single topical formulation, allowing both fibrous proteins to be synthesized simultaneously. This combination approach achieves comprehensive extracellular matrix reinforcement (collagen for structure, elastin for elasticity) in one application rather than requiring separate treatments, optimizing the quantity of active ingredients used.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The formulation activates the skin's own natural production of collagen and elastin through peptide signaling rather than introducing large quantities of external proteins. The tripeptides and tetrapeptides serve as molecular messengers that stimulate fibroblasts to synthesize endogenous collagen and elastin, dramatically reducing the quantity of substance needed compared to direct protein supplementation approaches.

Inventive Principle:
Principle #25Self-service

Data Source

PatentUS20250268808A1Topical composition and method of use
Publication Date: 2025.08.28 ALLERGAN SALES LLC
  • US20250268808A1 patent drawing
  • US20250268808A1 patent drawing
  • US20250268808A1 patent drawing

AI summary

The present invention relates to a topical composition that can be applied to a subject's outer skin such as abdominal area, neck area, chest area, arms, legs, or buttocks to treat skin laxity, cellulite and to firm, smooth and/or tone skin. The topical composition contains a tripeptide, a tetrapeptide and one or more botanical extracts.