Perfume-Cyclodextrin Complex Release Optimization

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Solution Overview

Problem

Current perfume compositions in cyclodextrin complexes are not optimized for release, resulting in less than 5% efficient release of perfume from the cyclodextrin complex, with most components remaining unexpressed and not providing the desired long-lasting fragrance.

Innovation Solution

A spray composition comprising a perfume-cyclodextrin complex with specific properties such as a cyclodextrin complex stability constant of less than 3.0, a ClogP of 2.5 or less, and a weight average molecular weight of 200 Daltons or less, along with a solvent and propellant, to enhance the release of perfume raw materials when exposed to moisture.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If current perfume compositions are used in cyclodextrin complexes, then the perfume can be encapsulated and provided for long-lasting fragrance, but less than 5% of the perfume components are released efficiently and most remain unexpressed

Engineering Contradiction:
Improveperfume release efficiencyVSAvoidcyclodextrin complex formulation
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent applies parameter changes by optimizing the cyclodextrin complex stability constant (log k) to be less than 3.0, controlling ClogP to be about 2.5 or less, and limiting weight average molecular weight to about 200 Daltons or less. These specific parameter adjustments enable significantly improved perfume release efficiency while maintaining the encapsulation benefits of cyclodextrin complexes.

Inventive Principle:
Principle #35Parameter changes

2Productivity

If perfume compositions are optimized for release from cyclodextrin complex, then release efficiency increases significantly, but specific formulation requirements must be met

Engineering Contradiction:
Improveperfume release rateVSAvoidperfume composition specification
Core Design Contradiction:
ProductivityVSManufacturing precision

Solution Approach 1:

The patent specifies precise parameter ranges for the perfume composition: cyclodextrin complex stability constant (log k) of less than 3.0, ClogP of about 2.5 or less, and weight average molecular weight of about 200 Daltons or less. These controlled parameters achieve high release efficiency (4 times or over 15 times greater than non-optimized compositions) while providing clear manufacturing specifications.

Inventive Principle:
Principle #35Parameter changes

3Stability of the object's composition

If perfume components have higher molecular weight or stronger binding to cyclodextrin, then they may be more stable in the complex, but they remain trapped and cannot be released effectively

Engineering Contradiction:
Improvecyclodextrin complex stabilityVSAvoidperfume expression
Core Design Contradiction:
Stability of the object's compositionVSReliability

Solution Approach 1:

The patent establishes an optimal balance by setting the cyclodextrin complex stability constant (log k) to less than 3.0, which maintains sufficient complex stability for encapsulation while allowing effective release. Additionally, the molecular weight is controlled to be about 200 Daltons or less, ensuring that perfume components are small enough to be released efficiently from the cyclodextrin cavity.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The optimized composition achieves a significant increase in perfume release, with the optimized formula showing 4 times the release of the original composition, and a specific example showing over 15 times the release of the non-optimized composition, providing a more noticeable and long-lasting fragrance to consumers.

Implementation Method 1

a cyclodextrin complex stability constant (log k) of less than about 3.0

Methodology Applied
Scientific EffectCyclodextrin complex stability:

Implementation Method 2

a propellant

Methodology Applied
Scientific EffectPhase change: Phase Change

Data Source

PatentEP3290087B1Spray compositions, sprayable products, and methods of treating a surface with the same
Publication Date: 2020.10.14 PROCTER & GAMBLE CO
  • EP3290087B1 patent drawingFigure 1
  • EP3290087B1 patent drawingFigure 2
  • EP3290087B1 patent drawingFigure 3

AI summary

A spray composition is provided. The spray composition includes a perfume-cyclodextrin complex, the perfume-cyclodextrin complex having perfume raw materials, wherein 10% or more, by weight of the perfume raw materials have: a cyclodextrin complex stability constant (log k) of less than about 3.0, a ClogP of about 2.5 or less; and a weight average molecular weight of about 200 Daltons or less; and cyclodextrin. The spray composition includes a solvent and less than 10 wt. % water, by weight of the total composition. A sprayable product including the spray composition and a method of treating a surface is provided.