Periodic Pattern Modulation for Detector-Limited Super-Resolution Imaging
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Solution Overview
Problem
Biomedical imaging modalities, such as PET, are limited by their intrinsic resolutions, making it difficult to effectively diagnose and treat certain diseases with high sensitivity and specificity, particularly in regions like the head-and-neck, pancreas, and brain, where small structures or delicate anatomy are present.
Innovation Solution
A method and apparatus that utilize a periodic pattern to modify the original image field before detection, followed by reconstruction to achieve a super-resolution image, surpassing the intrinsic resolution of the detector, using either physical movement or electronic modulation of the pattern.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If a standard detector is used for biomedical imaging, then the system is simple and cost-effective, but the imaging resolution is limited by the intrinsic resolution of the detector
Solution Approach 1:
A periodic pattern modulator is introduced as an intermediary component between the subject and the detector. This modulator applies a periodic modulation pattern to the image field, enabling super-resolution imaging without requiring a complex high-resolution detector. The modulator acts as a mediator that transforms the limited-capability detector into an effective super-resolution system through computational reconstruction algorithms.
2Measurement precision
If the intrinsic resolution of the detector is increased to achieve super-resolution imaging, then the imaging resolution improves, but the cost and complexity of the system increase significantly
Solution Approach 1:
Instead of changing the physical parameter of detector resolution, the invention changes the modulation parameter by applying a periodic pattern to the image field. This parameter change approach allows super-resolution imaging using standard detectors, avoiding the high cost of manufacturing high-resolution detectors while achieving the desired imaging resolution through computational methods.
3Measurement precision
If a periodic pattern modulator is added to achieve super-resolution imaging, then the imaging resolution improves beyond the detector's intrinsic limit, but the device complexity increases
Solution Approach 1:
The invention replaces complex mechanical high-resolution detector systems with a simpler periodic pattern modulator combined with computational reconstruction. Instead of relying on complex mechanical or optical systems to achieve high resolution, the method uses a relatively simple modulator that applies periodic patterns, with the complexity shifted to software-based reconstruction algorithms, thereby improving ease of operation.
Data Source
AI summary
The present disclosure describes various methods, systems, and storage medium for acquiring super-resolution images with modulation. An apparatus includes a periodic pattern and a detector. The periodic pattern is configured to move to modify an original image field before the original image field propagates onto the detector of an imaging system, the original image field originating from a subject and comprising information of the subject, and the detector is configured to detect the modified original image field to acquire a plurality of detected images. The apparatus also includes a memory storing instructions and a processor in communication with the memory. When the processor executes the instructions, the processor is configured to cause the apparatus to reconstruct a super-resolution image based on the plurality of detected images, wherein an imaging resolution of the super-resolution image is better than an intrinsic resolution of the detector.