Peripheral Nerve Stimulation for Cardiac Dysrhythmia and Hypertension

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Solution Overview

Problem

Current treatments for cardiac dysrhythmias and hypertension often have limited efficacy or require invasive procedures, and anti-arrhythmic medications can have significant side effects and drug interactions.

Innovation Solution

A noninvasive peripheral nerve stimulation system that uses a pulse generator and electrodes to deliver electrical stimulation to nerves in the limbs, modulating autonomic feedback loops to treat cardiac dysrhythmias and hypertension.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If anti-arrhythmic medications are used to treat cardiac dysrhythmias, then the frequency and duration of arrhythmias can be reduced, but significant side effects and drug interactions occur

Engineering Contradiction:

Improvetreatment efficacyVSAvoidside effects and drug interactions

Core Design Contradiction:

ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent replaces pharmacological treatment (chemical system) with electrical nerve stimulation (physical system). The peripheral nerve stimulator delivers electrical signals to modulate autonomic nervous system activity, thereby treating cardiac dysrhythmias without using medications that cause side effects and drug interactions.

Inventive Principle:

Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent introduces the autonomic nervous system as an intermediary between the treatment device and the heart. By stimulating peripheral nerves to modulate autonomic feedback loops, the treatment indirectly regulates cardiac rhythm, avoiding direct drug exposure to the heart and its associated side effects.

Inventive Principle:

Principle #24Intermediary (Mediator)

2Reliability

If invasive procedures are used to treat cardiac dysfunction, then treatment efficacy can be improved, but the complexity and risk of the procedure increases

Engineering Contradiction:

Improvetreatment efficacyVSAvoidprocedure invasiveness

Core Design Contradiction:

ReliabilityVSDevice complexity

Solution Approach 1:

The patent replaces invasive surgical or catheter-based procedures with noninvasive transcutaneous electrical stimulation. The peripheral nerve stimulator can be worn externally on the skin, eliminating the need for implants, incisions, or catheter insertions while maintaining therapeutic efficacy through modulation of autonomic nervous system activity.

Inventive Principle:

Principle #28Mechanics substitution (Replace mechanical system)

3Reliability

If electrical stimulation is delivered to modulate autonomic feedback loops, then blood pressure and arrhythmia frequency can be reduced, but the system complexity increases

Engineering Contradiction:

Improveblood pressure controlVSAvoidsystem complexity

Core Design Contradiction:

ReliabilityVSDevice complexity

Solution Approach 1:

The patent designs the peripheral nerve stimulator to perform multiple functions: delivering electrical stimulation to peripheral nerves, monitoring physiological responses, and modulating autonomic feedback loops to simultaneously treat both hypertension and cardiac dysrhythmias. This multi-functionality reduces the need for separate devices for blood pressure control and arrhythmia management.

Inventive Principle:

Principle #6Universality (Multi-functionality)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The system effectively reduces blood pressure, frequency and duration of cardiac arrhythmias, and can promote cardioversion, offering a potentially safer and more effective alternative to existing treatments.

Implementation Method 1

Methodology Applied

Scientific EffectElectrical stimulation: Conduction (electrical)

Data Source

PatentUS20250161685A1Systems and methods for treating cardiac dysfunction through peripheral nerve stimulation

Publication Date: 2025.05.22 CALA HEALTH INC

AI summary

Systems and methods are disclosed for the treatment and prevention of cardiac dysrhythmias and/or hypertension, and more specifically to systems and methods of treating cardiac dysrhythmias, including atrial fibrillation, as well as hypertension through noninvasive peripheral nerve stimulation.