Peristaltic Pump Calibration Using Correction Coefficients

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Solution Overview

Problem

Peristaltic pumps require frequent calibration due to mechanical stress on flexible tubes, leading to economic losses and inefficiencies, especially in applications requiring precision, as manual calibration methods waste fluid and are not accurate when conditions change.

Innovation Solution

An automated method for calibrating peristaltic pumps by pumping liquid into a calibration vessel, measuring the volume, and using correction coefficients stored in a control device to determine the calibrated volume per pumping cycle, allowing for precise adjustment and reuse of fluid, reducing waste and improving accuracy across varying operating conditions.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If manual calibration is performed by measuring volume or mass flow rate at different pump speeds, then calibration data can be obtained, but significant fluid is wasted causing economic losses

Engineering Contradiction:
Improvecalibration accuracyVSAvoidfluid waste
Core Design Contradiction:
Measurement precisionVSLoss of substance

Solution Approach 1:

The system uses feedback by measuring the actual volume pumped during calibration and using this information to calculate correction coefficients that adjust the pump's operational parameters. The calibration process itself provides feedback data that is used to improve future pumping accuracy without requiring additional fluid waste.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The patent performs preliminary calibration actions by determining correction coefficients during setup or maintenance phases rather than during every operational cycle. These pre-calculated coefficients are then applied during normal operation, eliminating the need for continuous fluid-wasting calibration measurements.

Inventive Principle:
Principle #10Preliminary action

2Ease of operation

If calibration is performed under different conditions than operating conditions (e.g., open vessel vs closed vessel), then calibration can be completed, but the calibration accuracy decreases for actual operation

Engineering Contradiction:
Improvecalibration convenienceVSAvoidcalibration accuracy
Core Design Contradiction:
Ease of operationVSMeasurement precision

Solution Approach 1:

The system compensates for different calibration and operating conditions by introducing correction coefficients that adjust for parameter changes such as vessel type, fluid properties, temperature, and pressure. These coefficients mathematically bridge the gap between calibration conditions and actual operating conditions, maintaining accuracy despite convenience-driven calibration setup differences.

Inventive Principle:
Principle #35Parameter changes

3Reliability

If the flexible tube is replaced frequently due to mechanical stress, then the pump can continue operating, but calibration must be repeated multiple times causing time loss and fluid waste

Engineering Contradiction:
Improvepump operational reliabilityVSAvoidcalibration time
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The system enables self-service by automatically calculating correction coefficients during calibration without requiring extensive manual intervention or repeated calibration cycles. The automated calculation and application of correction factors reduces the time and resources needed for recalibration after tube replacement, allowing the system to self-correct and minimize downtime.

Inventive Principle:
Principle #25Self-service

4Measurement precision

If multiple calibrations are performed to maintain precision under varying operating conditions, then accuracy is maintained, but large amounts of time are lost and fluid is wasted

Engineering Contradiction:
Improvedose accuracyVSAvoidoperational efficiency
Core Design Contradiction:
Measurement precisionVSProductivity

Solution Approach 1:

The system performs preliminary calibration to establish baseline correction coefficients that account for varying operating conditions. These pre-established coefficients are then applied across different operating scenarios, eliminating the need for multiple separate calibration events and maintaining productivity while preserving dose accuracy.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The correction coefficient system serves multiple functions: it calibrates the pump, compensates for tube wear, adjusts for different operating conditions, and maintains accuracy across various fluid properties. This multi-functional approach replaces multiple specialized calibration procedures with a single versatile calibration system.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The method enables precise calibration and operation of peristaltic pumps, minimizing fluid waste and economic losses by allowing automatic calibration and reuse of fluid, ensuring accuracy and efficiency throughout the pump's operating range.

Implementation Method 1

The rotation of the rotor and its respective rollers produces what is known as peristalsis, thus causing the fluid contained in the flexible tube or pipe to move forward.

Methodology Applied
Scientific EffectPeristalsis: Peristalsis

Data Source

PatentUS12163512B2Method for calibrating a peristaltic pump, method for dispensing a quantity of liquid by means of a peristaltic pump and device for producing sterile preparations that can execute said methods
Publication Date: 2024.12.10 GRIFOLS
  • US12163512B2 patent drawing
  • US12163512B2 patent drawing
  • US12163512B2 patent drawing

AI summary

A method is for calibrating a peristaltic pump, and for dispensing a quantity of liquid by a peristaltic pump. A device for producing sterile preparations can execute the methods.