Peritoneal Dialysis Catheter Sensor for Real-Time Analyte Monitoring
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Solution Overview
Problem
Current devices lack the capability to continuously and accurately detect and quantify analytes such as glucose, hydrogen ion, and creatinine in peritoneal fluid during peritoneal dialysis, which is crucial for monitoring treatment progress and making informed medical decisions in real-time.
Innovation Solution
A device comprising a catheter with sensors attached to detect analytes in peritoneal fluid, connected to a main control unit that receives, stores, and transmits data to external devices for real-time monitoring and analysis, allowing for timely interventions based on analyte concentrations and their changes over time.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If sensors are attached to the catheter for analyte detection, then measurement precision is improved, but device complexity increases
Solution Approach 1:
The sensor is integrated directly onto the catheter structure, merging the detection function with the existing catheter. This allows analyte detection in the peritoneal fluid without requiring separate detection devices, thereby improving measurement precision while minimizing the increase in overall device complexity.
Solution Approach 2:
The catheter serves multiple functions: it acts as both a fluid delivery/drainage device and a sensor platform for analyte detection. By making the catheter multi-functional, the invention avoids adding separate dedicated detection devices, thus improving measurement capability while controlling device complexity.
2Reliability
If continuous real-time monitoring is implemented, then reliability is improved, but use of energy increases
Solution Approach 1:
The sensor provides continuous real-time monitoring of analyte concentrations in the peritoneal fluid throughout the dialysis process. This continuous detection capability improves reliability by enabling timely detection of treatment issues, while the sensor design optimizes power consumption to manage energy usage during extended monitoring periods.
Solution Approach 2:
The system implements real-time feedback by continuously monitoring analyte levels and transmitting data to external devices. This feedback mechanism improves treatment reliability by enabling immediate detection of abnormalities, while the feedback system is designed to minimize energy consumption through efficient data transmission protocols and processing.
3Measurement precision
If multiple sensors are added for different analytes, then measurement precision is improved, but device complexity increases
Solution Approach 1:
Multiple sensors for detecting different analytes (glucose, creatinine, pH) are integrated onto a single catheter structure. This merging approach enables multi-analyte detection with improved measurement precision while avoiding the complexity of requiring separate catheters or devices for each analyte.
Solution Approach 2:
The catheter system is designed with multi-functionality to detect multiple analytes simultaneously. By incorporating multiple sensing capabilities into one device, the system achieves comprehensive monitoring of treatment parameters without proportionally increasing device complexity.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Enables continuous, real-time monitoring of analytes in peritoneal fluid, facilitating informed medical decisions and improving the efficiency and safety of peritoneal dialysis by providing immediate feedback on treatment progress and potential issues.
Implementation Method 1
The sensor is configured to contact the peritoneal fluid and to detect and quantify the concentrations of analytes in the peritoneal fluid
Data Source
AI summary
A device for in vivo detecting and quantifying a concentration of an analyte in a peritoneal fluid of a subject. The device includes (a) a catheter having an open proximal end configured to be disposed external to the subject, an open distal end configured to be disposed within the peritoneal cavity comprising the peritoneal fluid, an anchor portion, an outer wall, and an inner wall, (b) a sensor disposed adjacent to the open distal end and configured to detect and quantify the concentration of the analyte in the peritoneal fluid, and (c) a main control unit disposed external to the subject, connected to the sensor via a wire, and configured to control the sensor, receive and store detection and quantification data from the sensor, and transmit the data to a second device. A portion of the wire is disposed between the inner wall and the outer wall of the catheter.