Peritoneal Dialysis Apparatus with Intraperitoneal Pressure Feedback
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Solution Overview
Problem
Peritoneal dialysis is less efficient than hemodialysis and can lead to peritoneal membrane function decline over time, necessitating optimization of therapy parameters to maximize efficiency and minimize membrane decay.
Innovation Solution
An apparatus for peritoneal dialysis that includes a measurement device for intraperitoneal pressure and a control unit to manage fill-and-measurement or drain-and-measurement steps, establishing a function of pressure by added volume to determine patient-specific characteristics and generate therapy-related predictions or recommendations for optimizing therapy parameters.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Ease of operation
If peritoneal dialysis is used instead of hemodialysis, then patients can be treated at home with greater freedom, but therapy efficiency is reduced
Solution Approach 1:
The system continuously measures intraperitoneal pressure during dialysis fluid exchange and uses this feedback to automatically adjust therapy parameters such as fill volume, dwell time, and exchange frequency. This closed-loop control optimizes ultrafiltration efficiency while maintaining patient comfort and home treatment capability.
Solution Approach 2:
The dialysis machine dynamically adjusts therapy parameters based on real-time pressure measurements and patient response. The system transitions from fixed static protocols to adaptive dynamic treatment, modifying fill volumes and exchange rates during the therapy course to maximize efficiency while preserving home treatment benefits.
2Duration of action of stationary object
If peritoneal dialysis is performed over extended periods, then continuous treatment is possible, but peritoneal membrane function declines over time
Solution Approach 1:
The system performs preliminary pressure measurements during each dialysis exchange to assess membrane function status before proceeding with the full therapy cycle. By detecting early signs of membrane stress or dysfunction, the system can proactively adjust subsequent treatment parameters to prevent further degradation and extend the functional life of the peritoneal membrane.
Solution Approach 2:
The continuous monitoring of intraperitoneal pressure provides real-time feedback on membrane function. The system uses this information to adaptively modify therapy intensity and duration, reducing stress on the membrane when signs of fatigue are detected while maintaining adequate treatment efficacy, thereby extending the可持续性 of peritoneal dialysis.
3Device complexity
If standard fixed therapy parameters are used, then treatment protocol is simple, but therapy efficiency is not maximized
Solution Approach 1:
The dialysis machine autonomously optimizes therapy parameters by automatically analyzing pressure measurement data and adjusting treatment protocols without requiring complex manual programming by the patient or clinician. The system performs self-optimization through embedded algorithms that interpret pressure trends and modify fill volumes, dwell times, and exchange frequencies to maximize efficiency while keeping the user interface simple.
4Measurement precision
If pressure measurements are taken continuously during fluid flow, then real-time data is obtained, but measurement accuracy is reduced due to flow interference
Solution Approach 1:
The system employs periodic measurement cycles where pressure is measured during brief pause intervals between filling and draining phases. This periodic sampling strategy captures representative pressure data while avoiding the confounding effects of active fluid flow, maintaining measurement accuracy without significantly extending total therapy time through efficient use of existing treatment pauses.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This approach enhances therapy efficiency, improves membrane function tracking, and provides early warnings for issues like peritonitis, while optimizing fluid exchange and ultrafiltration, thereby extending the effectiveness of peritoneal dialysis.
Implementation Method 1
a measurement device for measuring the fluid pressure of the delivered dialysis fluid and/or the fluid pressure in the peritoneal cavity (intraperitoneal pressure)
Implementation Method 2
The peritoneal membrane acts as membrane for removing waste and excess water from the blood
Implementation Method 3
The peritoneal membrane acts as membrane for removing waste and excess water from the blood
Implementation Method 4
Peritoneal dialysis machines without pumps are gravity driven, i.e. the movement of the dialysis fluid is caused by gravity
Data Source
AI summary
The present invention relates to an apparatus for performing peritoneal dialysis, the apparatus comprising means for delivering dialysis fluid to the peritoneal cavity of a patient, a measurement device for measuring the fluid pressure of the delivered dialysis fluid and/or the fluid pressure in the peritoneal cavity, i.e. the intraperitoneal pressure and/or any pressure related thereto, and a control unit operably connected to said means and the measurement device, wherein the control unit is configured to effect an inflow or outflow phase encompassing a series of fill-and-measurement or drain-and-measurement steps, each step comprising delivering a predetermined quantity of dialysis fluid to the peritoneal cavity or draining a predetermined quantity of dialysis fluid from the peritoneal cavity and subsequently measuring and recording a pressure value.