Permeable Spreading Layer for Liquid Analysis

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Solution Overview

Problem

Existing permeable spreading layers for liquid analysis face challenges with low reflectivity, mechanical robustness, and environmental concerns, while requiring effective sample distribution and homogeneity for accurate analytical assays.

Innovation Solution

A permeable spreading layer comprising hollow glass microspheres and a polymeric binder, which provides high reflectivity, low density, and mechanical resistance, along with additional components like buffers, surfactants, and voiding agents to enhance layer formation and sample distribution.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Difficulty of detecting and measuring

If polymeric particles are used for permeable spreading layers, then permeability and sample distribution are improved, but reflectivity and mechanical robustness deteriorate

Engineering Contradiction:
Improvesample distributionVSAvoidreflectivity
Core Design Contradiction:
Difficulty of detecting and measuringVSIllumination intensity

Solution Approach 1:

The patent combines polymeric particles with inorganic reflective particles (such as titanium dioxide, barium sulfate, or zinc oxide) to create a composite spreading layer. This composite structure maintains the permeability and sample distribution properties of polymeric particles while adding the high reflectivity of inorganic particles, thereby resolving the contradiction between sample distribution and reflectivity.

Inventive Principle:
Principle #40Composite materials

2Difficulty of detecting and measuring

If polymeric particles are used for permeable spreading layers, then permeability and sample distribution are improved, but mechanical robustness deteriorates

Engineering Contradiction:
Improvesample distributionVSAvoidmechanical robustness
Core Design Contradiction:
Difficulty of detecting and measuringVSStrength

Solution Approach 1:

The combination of polymeric particles with inorganic particles creates a composite structure where the inorganic particles provide mechanical strength and structural integrity while the polymeric particles maintain permeability. This composite approach allows the spreading layer to withstand mechanical stresses during manufacturing and use while effectively distributing samples.

Inventive Principle:
Principle #40Composite materials

3Illumination intensity

If inorganic particles (TiO2, BaSO4, CaCO3) are used for spreading layers, then reflectivity is improved, but manufacturability and process control deteriorate

Engineering Contradiction:
ImprovereflectivityVSAvoidprocess control
Core Design Contradiction:
Illumination intensityVSEase of manufacture

Solution Approach 1:

By combining inorganic reflective particles with polymeric particles, the patent creates a composite system where the polymeric component improves coat-ability and process control while the inorganic component provides reflectivity. The polymeric particles act as a binder and processing aid, making the mixture easier to handle and apply uniformly during manufacturing.

Inventive Principle:
Principle #40Composite materials

4Illumination intensity

If hollow glass microspheres are used, then reflectivity and low density are improved, but manufacturing robustness may deteriorate

Engineering Contradiction:
ImprovereflectivityVSAvoidmanufacturing robustness
Core Design Contradiction:
Illumination intensityVSEase of manufacture

Solution Approach 1:

The patent combines hollow glass microspheres with polymeric particles to create a composite spreading layer. The polymeric component provides mechanical robustness and processability, while the hollow glass microspheres contribute high reflectivity and low density. This composite approach balances the advantages and disadvantages of each material type.

Inventive Principle:
Principle #40Composite materials

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The solution achieves effective distribution and analysis of aqueous samples with high reflectivity and mechanical robustness, minimizing environmental concerns and ensuring homogeneous sample concentration for accurate analytical results.

Implementation Method 1

hollow glass microspheres and a polymeric binder, in which the polymeric spreading layer has high reflectivity

Methodology Applied
Scientific EffectReflection: Reflection

Implementation Method 2

For a layer to receive, and then spread and distribute a sample to layer(s) below, it must be permeable, i.e., have pores through which the sample can flow

Methodology Applied
Scientific EffectCapillary action: Capillary Action

Data Source

PatentUS20250091044A1Sample Spreading and Loading Layer for Dry Slide
Publication Date: 2025.03.20 IDEXX LABORATORIES INC
  • US20250091044A1 patent drawing
  • US20250091044A1 patent drawing
  • US20250091044A1 patent drawing

AI summary

Highly reflective, low density, permeable spreading layers for the transport, manipulation and analysis of liquid are provided, as well as articles that incorporate one or more of such permeable spreading layers and related methods.