Peroxide Whitening Stability via Block Copolymer and Insoluble Phosphate

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Solution Overview

Problem

Conventional oral care products with peroxide whitening agents face stability issues due to the high reactivity of peroxides, which limits their effectiveness in maintaining teeth whiteness and preventing stains.

Innovation Solution

An oral care composition incorporating a block copolymer of ethylene oxide and propylene oxide as a vehicle, combined with an abrasive system of insoluble phosphate salts like sodium metaphosphate and calcium pyrophosphate, enhances the stability of peroxide whitening agents without the need for encapsulation or film-type materials.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Stability of the object's composition

If conventional stabilizing components are used to stabilize peroxides, then peroxide stability is improved, but the effectiveness is still limited due to the high reactivity of peroxides

Engineering Contradiction:

Improveperoxide stabilityVSAvoideffectiveness of stabilizing components

Core Design Contradiction:

Stability of the object's compositionVSReliability

Solution Approach 1:

The patent introduces a specific stabilizing component that acts as an intermediary between the peroxide and other formulation ingredients. This stabilizer forms a protective complex with the peroxide, reducing its reactivity toward destabilizing agents while maintaining its whitening effectiveness. The stabilizer mediates the interaction between peroxide and the oral care formulation, preventing degradation pathways.

Inventive Principle:

Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent optimizes the concentration of the stabilizing component within a specific range (0.1-5% weight/weight) to achieve maximum peroxide stability. By carefully controlling the stabilizer concentration parameter, the formulation achieves enhanced peroxide stability without compromising the whitening performance or creating unwanted side effects. This parameter optimization resolves the contradiction between stability and effectiveness.

Inventive Principle:

Principle #35Parameter changes

2Stability of the object's composition

If peroxides are combined with stabilizing components, then peroxide stability is improved, but the reactivity of peroxides remains high

Engineering Contradiction:

Improveperoxide stabilityVSAvoidreactivity of peroxides

Core Design Contradiction:

Stability of the object's compositionVSObject-affected harmful factors

Solution Approach 1:

The stabilizing component serves as a protective intermediary that reduces the harmful reactivity of peroxides. It forms a stabilizing complex that shields the peroxide from reacting with unwanted substances in the formulation and in the oral cavity, thereby reducing harmful side reactions while maintaining the desired whitening effect.

Inventive Principle:

Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent converts the high reactivity of peroxides, which is normally a harmful factor leading to degradation, into a beneficial feature. The stabilizing component harnesses the reactivity of peroxides to maintain their whitening effectiveness while directing it away from degradation pathways. The reactive nature of peroxides is preserved for the desired function while being protected from harmful reactions.

Inventive Principle:

Principle #22Blessing in disguise (Convert harm into benefit)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This composition significantly increases peroxide stability while maintaining teeth cleaning performance, as demonstrated by the pellicle cleaning ratio greater than or equal to 80, and prevents stains on teeth, even under accelerated aging conditions.

Implementation Method 1

an orally acceptable vehicle including a block copolymer of ethylene oxide and propylene oxide

Methodology Applied

Scientific EffectSolvation: Solvation

Implementation Method 2

conventional toothpastes including peroxides (e.g., hydrogen peroxide) are often utilized to oxidize chromophores bound to surfaces of teeth to thereby whiten the teeth

Methodology Applied

Scientific EffectOxidation: Oxidation

Implementation Method 3

an abrasive system including at least one insoluble phosphate salt

Methodology Applied

Scientific EffectAbrasion: Abrasion

Data Source

PatentUS10517804B2Whitening compositions and methods for increasing stability of the same

Publication Date: 2019.12.31 COLGATE PALMOLIVE CO

AI summary

Oral care compositions and methods for whitening and preventing stains on teeth are provided. The oral care composition may include an orally acceptable vehicle, a peroxide whitening agent, and an abrasive system. The orally acceptable vehicle may include a block copolymer of ethylene oxide and propylene oxide, and the abrasive system may include at least one insoluble phosphate salt.