Personalized Cognitive Treatment Recommendations From Patient Data

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Solution Overview

Problem

Existing technologies lack personalized and effective cognitive treatment solutions for immune-mediated and neuro-degenerative disorders, leading to inadequate remediation therapies due to heterogeneous lesion patterns and varying cognitive impairments among patients.

Innovation Solution

A system and method for generating personalized cognitive treatment recommendations using a predictive model trained on clinical and physiological data, incorporating cognitive treatment tools and monitoring components, to adapt treatment regimens based on individual cognitive profiles and disease progression.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If standardized cognitive treatment protocols are used for immune-mediated and neuro-degenerative disorders, then treatment delivery is simplified and more accessible, but treatment efficacy is reduced due to heterogeneous lesion patterns and varying cognitive impairments among patients

Engineering Contradiction:
Improvetreatment delivery simplicityVSAvoidtreatment efficacy
Core Design Contradiction:
Ease of operationVSReliability

Solution Approach 1:

The system dynamically adapts treatment protocols based on real-time cognitive assessment data and individual patient characteristics. Treatment parameters such as task difficulty, session duration, and intervention type are automatically adjusted according to measured cognitive performance, allowing the standardized platform to respond to individual variability without requiring complex manual customization

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The system modifies treatment parameters including task complexity, cognitive domain focus, and intervention intensity based on individual cognitive profiles derived from baseline assessments and ongoing monitoring. This allows the same standardized platform to deliver personalized treatments by changing operational parameters rather than requiring entirely different treatment protocols

Inventive Principle:
Principle #35Parameter changes

2Reliability

If personalized cognitive treatment regimens are developed for each patient, then treatment efficacy is improved by addressing specific cognitive impairments, but system complexity and resource requirements increase significantly

Engineering Contradiction:
Improvetreatment efficacyVSAvoidsystem complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The personalized treatment system is segmented into modular components: cognitive assessment modules, analysis modules, and treatment delivery modules. Each module operates independently but integrates through standardized interfaces, allowing personalized treatment to be achieved through coordinated simple components rather than a single complex system

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The system automatically generates personalized treatment regimens by processing cognitive assessment data through algorithms that identify impairment patterns and select appropriate interventions. This self-service capability eliminates the need for manual treatment customization by clinicians, achieving personalization without proportionally increasing system complexity

Inventive Principle:
Principle #25Self-service

3Adaptability or versatility

If cognitive treatment monitoring and adjustment are implemented continuously, then treatment adaptation to disease progression is improved, but time and resource consumption increase

Engineering Contradiction:
Improvetreatment adaptation capabilityVSAvoidmonitoring time
Core Design Contradiction:
Adaptability or versatilityVSLoss of time

Solution Approach 1:

The system implements periodic cognitive monitoring at scheduled intervals rather than continuous monitoring, with treatment adjustments made at these discrete time points. This periodic approach maintains adaptability to disease progression while minimizing time and resource consumption by avoiding constant assessment and adjustment cycles

Inventive Principle:
Principle #19Periodic action

Solution Approach 2:

The system uses automated feedback loops where cognitive assessment results are immediately processed to generate treatment adjustment recommendations. This rapid feedback mechanism enables effective adaptation without prolonged monitoring periods, as the system quickly translates assessment data into actionable treatment modifications

Inventive Principle:
Principle #23Feedback

Data Source

PatentUS20250336498A1Cognitive screens, monitor and cognitive treatments targeting immune-mediated and neuro-degenerative disorders
Publication Date: 2025.10.30 AKILI INTERACTIVE LABS INC
  • US20250336498A1 patent drawing
  • US20250336498A1 patent drawing
  • US20250336498A1 patent drawing

AI summary

Systems and methods for generating a personalized cognitive treatment recommendation for an individual. The system includes one or more processors; and a memory to store processor-executable instructions. Upon execution of the instructions, the one or more processors receive parameters for at least one cognitive treatment tool; receive physiological data indicative of a condition of the individual, and/or clinical data associated with the individual; and generate the personalized cognitive treatment recommendation based on the physiological data and/or the clinical data. The recommendation includes a specification of (i) at least one first cognitive treatment tool, (ii) at least one second cognitive treatment tool different from the at least one first cognitive treatment tool, or (iii) both (i) and (ii). Optionally, the one or more processors receive performance data indicative of the individual's performance of at least one task associated with the at least one cognitive treatment tool of the recommendation.