Personalized Shock Wave Therapy for Ischemic Tissue Healing

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Solution Overview

Problem

Conventional acoustic pressure shock wave treatments for tissue conditions are not personalized to account for patient-specific comorbidities, health status, and biometrics, leading to suboptimal healing outcomes, particularly in cases of poor blood circulation and ischemic conditions.

Innovation Solution

The use of personalized acoustic pressure shock wave therapy that adjusts dosage and treatment parameters based on individual patient factors such as cardiovascular health, diabetes status, blood flow, and tissue oxygenation to enhance tissue regeneration and healing.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If conventional fixed acoustic pressure shock wave treatment regimens are used, then treatment simplicity is maintained, but treatment effectiveness deteriorates due to lack of personalization for patient-specific factors

Engineering Contradiction:
Improvetreatment effectivenessVSAvoidtreatment regimen complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The treatment regimen dynamically adjusts acoustic pressure shock wave parameters (dosage, energy levels, treatment frequency) based on patient-specific factors including comorbidities, biometrics, and real-time tissue response measurements. This transforms the static fixed protocol into a dynamic personalized treatment plan that adapts to individual patient needs.

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The system changes multiple treatment parameters simultaneously based on patient characteristics: dosage is adjusted according to comorbidities and tissue oxygenation levels, energy levels are modified based on blood flow measurements, and treatment frequency is adapted to patient-specific healing rates. This multi-parameter adjustment enables personalized treatment while maintaining systematic control.

Inventive Principle:
Principle #35Parameter changes

2Productivity

If higher acoustic pressure shock wave dosage is applied to accelerate healing, then treatment speed increases, but risk of tissue damage increases

Engineering Contradiction:
Improvehealing speedVSAvoidtissue damage risk
Core Design Contradiction:
ProductivityVSObject-affected harmful factors

Solution Approach 1:

The system implements real-time feedback monitoring of tissue response during acoustic pressure shock wave treatment. Sensors measure parameters such as tissue oxygenation, blood flow changes, and cellular response to adjust dosage dynamically. This closed-loop feedback mechanism allows the system to accelerate healing when tissue responds well while immediately reducing dosage when signs of tissue stress or damage appear.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The treatment protocol uses progressive dosage escalation, starting with lower doses to assess tissue tolerance and gradually increasing to optimal therapeutic levels. This staged approach allows the system to apply sufficient dosage to accelerate healing while staying within safe thresholds determined by real-time tissue response monitoring.

Inventive Principle:
Principle #16Partial or excessive action

3Reliability

If treatment parameters are customized for each patient, then treatment effectiveness improves, but treatment time and complexity increase

Engineering Contradiction:
Improvehealing outcome qualityVSAvoidtreatment planning time
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The system performs preliminary assessment of patient factors (comorbidities, biometrics, tissue characteristics) before treatment begins, using this information to pre-calculate personalized treatment parameters. This preliminary customization eliminates the need for time-consuming adjustments during treatment sessions while ensuring each patient receives an optimized regimen from the start.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The system automatically generates personalized treatment protocols by integrating patient data from electronic health records, biometric sensors, and tissue analysis instruments. This self-service capability eliminates manual treatment planning time while maintaining high levels of personalization, as the system autonomously synthesizes optimal parameters based on accumulated patient information.

Inventive Principle:
Principle #25Self-service

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach improves wound healing by increasing blood perfusion, reducing inflammation, and promoting vascularization, leading to more effective treatment of chronic and acute tissue conditions without causing tissue damage.

Implementation Method 1

acoustic pressure shock waves demonstrated positive results in treating different soft or hard tissues with ischemic conditions and for healing diverse chronic wounds

Methodology Applied
Scientific EffectAcoustic pressure shock waves: Shock Wave

Implementation Method 2

applying acoustic pressure shock waves to cause localized trauma, including micro-disruptions, non-osseous tissue stimulation, increased vascularization, and circulation

Methodology Applied
Scientific EffectMechanical disruption: Impact Force

Implementation Method 3

The acoustic pressure shock waves have a compressive phase (produces high compressive pressures) and a tensile phase (produces cavitation bubbles that collapse with high speed jets)

Methodology Applied
Scientific EffectCavitation: Cavitation

Data Source

PatentUS10888715B2Acoustic pressure shock waves used for personalized medical treatment of tissue conditions
Publication Date: 2021.01.12 SANUWAVE INC
  • US10888715B2 patent drawing
  • US10888715B2 patent drawing
  • US10888715B2 patent drawing

AI summary

A system for individualized treatment of a tissue condition with acoustic pressure shocks includes personalized determination and automatic adjustment of a shock wave treatment regimen or shock wave dosage to be administered for personalized treatment based on factors such as a patient's comorbidities, state of the tissue condition, individual physical characteristics and lifestyle parameters.