Personalized Supplement Formulation Using Biomarkers and Feedback

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Solution Overview

Problem

Existing nutritional supplement approaches fail to provide personalized formulations tailored to the unique biological and athletic profiles of individual athletes, lacking integration of advanced genetic and metabolic data for optimal performance enhancement.

Innovation Solution

A method and system that utilizes genetic testing, blood metabolomic analysis, lipidomics, and urine analysis to create personalized nutritional supplement formulations, incorporating machine learning for adaptive and iterative refinement based on user data and feedback.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If personalized nutritional supplement formulations are created using advanced genetic and metabolic data analysis, then the effectiveness and suitability of supplements for individual athletes is improved, but the complexity of the system and cost of implementation increases

Engineering Contradiction:
Improveeffectiveness of supplement formulationsVSAvoidsystem complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The system segments the nutritional supplement market into personalized formulations based on individual genetic profiles, metabolic data, and athletic performance requirements. Each athlete receives a customized supplement package rather than a generic formulation, dividing the universal supplement problem into individualized solutions that address specific biological needs.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The system changes multiple parameters simultaneously including genetic markers, metabolic rates, nutrient absorption efficiency, and performance goals to create optimized supplement formulations. By adjusting these parameters based on individual data, the system transforms standard supplement compositions into personalized formulations that maximize effectiveness.

Inventive Principle:
Principle #35Parameter changes

2Measurement precision

If multiple types of biological data collection and analysis are performed, then the precision of nutritional recommendations is improved, but the time and resources required for analysis increase

Engineering Contradiction:
Improveprecision of nutritional recommendationsVSAvoidtime for data analysis
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The system performs preliminary data collection and analysis by gathering genetic information, metabolic profiles, and performance metrics before formulating supplement recommendations. This advance preparation creates a comprehensive baseline that enables rapid, precise recommendations without requiring extensive analysis at the point of decision-making.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The system implements continuous feedback loops where performance data and biological measurements are constantly monitored and fed back into the formulation algorithm. This ongoing feedback refines the precision of recommendations over time while streamlining the analysis process through learned patterns and established baselines.

Inventive Principle:
Principle #23Feedback

3Adaptability or versatility

If dynamic and adaptive supplement protocols are implemented, then the ability to optimize performance over time is improved, but the complexity of monitoring and adjustment increases

Engineering Contradiction:
Improveability to optimize performanceVSAvoidcomplexity of monitoring
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The system transitions from static supplement formulations to dynamic protocols that automatically adjust based on changing performance metrics, biological markers, and training demands. Supplement compositions, dosages, and timing are made adaptable through continuous monitoring and real-time modifications driven by performance feedback and biological data.

Inventive Principle:
Principle #15Dynamics

Data Source

PatentUS20260074049A1Tailored nutritional supplements for athletic performance
Publication Date: 2026.03.12 OPTIGENIX
  • US20260074049A1 patent drawing
  • US20260074049A1 patent drawing
  • US20260074049A1 patent drawing

AI summary

A personalized supplement formulation system integrates biological data, structured qualitative feedback, and machine learning algorithms to generate individualized nutritional protocols. The system receives biological inputs such as genetic single nucleotide polymorphism (SNP) data, blood biomarkers (e.g., ferritin, vitamin D, B12), lipid profiles, and urinary metabolites. A digital user profile is created by organizing these inputs and calculating derived indices relevant to supplementation. Structured qualitative feedback, including dietary restrictions, perceived wellness, and training goals, is normalized and processed alongside the biological data. A trained machine learning engine analyzes combined inputs to output a tailored supplement formulation specifying ingredient selection, dosage, delivery format, and timing. Instructions are transmitted to a manufacturing system capable of producing the custom formulation. The system supports periodic re-evaluation and iteration based on new biological samples or user-reported feedback, enabling dynamic personalization over time and improving efficacy, compliance, and outcome tracking in athletic and wellness domains.