PET Scan Acquisition Time Optimization via Dynamic Count Rate Feedback

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Solution Overview

Problem

Current PET scan planning is not optimized for individual patients, leading to uncertainties due to variables like dose calibration errors, clock synchronization issues, and variations in fludeoxyglucose urine clearance, resulting in inconsistent image quality and potentially higher radiation exposure.

Innovation Solution

A method that adjusts the PET imaging data acquisition time based on the measured count rate, using initial count rates and historical data to optimize acquisition times, ensuring uniform image quality across different table positions and accounting for patient-specific factors.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If predetermined look-up-table is used to decide injected dose based on patient BMI, then dose prescription is simplified, but adaptability to patient-specific variations (dose calibration error, clock synchronization error, FDG urine clearance) is lost

Engineering Contradiction:
Improvedose prescriptionVSAvoidadaptability to patient-specific variations
Core Design Contradiction:
Ease of operationVSAdaptability or versatility

Solution Approach 1:

The system measures the actual count rate during the PET scan acquisition and uses this feedback to dynamically adjust the acquisition time. This closed-loop feedback mechanism compensates for patient-specific variations such as dose calibration errors, clock synchronization errors, and FDG urine clearance differences, resolving the contradiction between simplified operation and adaptability to individual patient variations.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The acquisition time is changed from a fixed predetermined value to a dynamic parameter that adjusts in real-time based on measured count rates. This dynamic adjustment allows the system to adapt to each patient's specific conditions while maintaining ease of operation through automated control.

Inventive Principle:
Principle #15Dynamics

2Productivity

If fixed acquisition time per table position is used, then scanning workflow is simplified, but image quality consistency across different patients and conditions cannot be ensured

Engineering Contradiction:
Improvescanning workflow efficiencyVSAvoidimage quality consistency
Core Design Contradiction:
ProductivityVSManufacturing precision

Solution Approach 1:

The system continuously monitors the count rate during acquisition and uses this information to adjust the acquisition time dynamically. This feedback mechanism ensures that each patient receives the precise acquisition time needed for optimal image quality, eliminating the trade-off between workflow efficiency and image quality consistency.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The acquisition time parameter is changed from a fixed value to a variable that adjusts based on measured count rates. This parameter change allows the system to maintain consistent image quality across different patients and conditions while preserving scanning workflow efficiency through automated real-time adjustment.

Inventive Principle:
Principle #35Parameter changes

3Manufacturing precision

If higher injected dose is administered to ensure sufficient counts, then image quality for diagnosis is improved, but radiation exposure to patient increases

Engineering Contradiction:
Improveimage qualityVSAvoidradiation exposure
Core Design Contradiction:
Manufacturing precisionVSObject-affected harmful factors

Solution Approach 1:

The system measures the actual count rate during acquisition and dynamically adjusts the acquisition time to achieve the target count level. This feedback-controlled approach eliminates the need to administer higher doses as a safety margin, thereby reducing radiation exposure while maintaining diagnostic image quality.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The system uses the patient's own measured count rate to determine the optimal acquisition time, allowing each patient's scan to be self-adjusted to the precise minimum time needed for diagnostic quality images, thereby minimizing unnecessary radiation exposure.

Inventive Principle:
Principle #25Self-service

4Reliability

If longer acquisition time is used to compensate for count level variations, then sufficient counts for reliable image reconstruction are achieved, but scan time increases

Engineering Contradiction:
Improveimage reconstruction reliabilityVSAvoidscan time
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The system dynamically adjusts acquisition time based on real-time count rate measurements, ensuring that each patient receives the precise minimum time needed for reliable image reconstruction. This eliminates the need to use longer acquisition times as a blanket compensation strategy, thereby maintaining reconstruction reliability while minimizing scan time.

Inventive Principle:
Principle #23Feedback

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach improves image quality and reduces scan time by dynamically adjusting acquisition times, compensating for errors and variations, and allows for personalized dose optimization, potentially reducing radiation exposure.

Implementation Method 1

positron emission tomography (PET) imaging arts

Methodology Applied
Scientific EffectPositron emission: Radioactive Decay

Implementation Method 2

acquiring emission imaging data using an emission image acquisition device

Methodology Applied
Scientific EffectGamma ray detection: Absorption (EM radiation)

Data Source

PatentUS11311263B2Automatic on-the-fly positron emission tomography (PET) scan planning and optimization
Publication Date: 2022.04.26 KONINKLIJKE PHILIPS NV
  • US11311263B2 patent drawing
  • US11311263B2 patent drawing
  • US11311263B2 patent drawing

AI summary

A non-transitory computer-readable medium stores instructions executable by a processor to perform an acquisition and reconstruction method for a first image acquisition device. The method includes determining a scheduled acquisition time based on an attenuation map derived from imaging data from a second image acquisition device and a sensitivity matrix of the first image acquisition device; acquiring emission imaging data using the first image acquisition device, where the acquiring is scheduled to be performed over the scheduled acquisition time; during an initial portion of the acquiring, measuring a count or count rate of the acquired emission imaging data; adjusting the scheduled acquisition time based on the measured count or count rate to generate an adjusted acquisition time while continuing the acquiring; stopping the acquiring at the adjusted acquisition time; and reconstructing the emission imaging data acquired over the adjusted acquisition time to generate one or more reconstructed images.